INT184240

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Context Info
Confidence 0.27
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 3.58
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Egf) plasma membrane (Egf)
Anatomy Link Frequency
HGF 2
Egf (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 99 99.62 Very High Very High Very High
cytokine 66 92.92 High High
Arthritis 47 90.28 High High
imagery 10 83.12 Quite High
Inflammation 36 55.48 Quite High
chemokine 24 39.60 Quite Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Rheumatism 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 201 99.76 Very High Very High Very High
Rheumatoid Arthritis 99 99.62 Very High Very High Very High
Synovitis 21 94.56 High High
Seronegative Spondarthritis 12 90.28 High High
Disease 39 89.92 High High
Arthritis 46 86.76 High High
Inflammatory Bowel Disease 2 86.04 High High
INFLAMMATION 16 55.48 Quite High
Breast Cancer 7 5.00 Very Low Very Low Very Low
Aggression 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients with early RA had significantly elevated synovial levels of IL-2, IL-4, IL-13, IL-17, EGF and bFGF when compared with patients with established RA (Figs 1 and 2, and Table 2).
Positive_regulation (elevated) of Localization (levels) of EGF associated with rheumatoid arthritis
1) Confidence 0.27 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175027 Disease Relevance 2.22 Pain Relevance 0.95
Growth factors stain in patches that do not correlate with the more sparse staining patterns of the TAF markers themselves due to the fact that the tumor cells also secrete the growth factors HGF, IL-6 and EGF in the presence of MSC as demonstrated by in vitro co-culture data (Figure S4).


Positive_regulation (presence) of Localization (secrete) of EGF in HGF associated with cancer
2) Confidence 0.25 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2661372 Disease Relevance 1.36 Pain Relevance 0.04

General Comments

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