INT184242

Context Info Confidence 0.03 First Reported 2005 Last Reported 2005 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.87 Pain Relevance 0.56

extracellular space (Csf2) mitochondrion (Mthfd1) extracellular region (Csf2) oxidoreductase activity (Mthfd1) ligase activity (Mthfd1) cytoplasm (Mthfd1)

Anatomy Link Frequency monocytes 2 Mthfd1 (Mus musculus) Csf2 (Mus musculus)

Pain Link Frequency Relevance Heat rheumatoid arthritis 99 95.36 Arthritis 47 87.88 Inflammation 36 87.48 cytokine 63 85.12 chemokine 21 69.68 Rheumatism 2 5.00 Osteoarthritis 2 5.00 fibrosis 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Disease 39 98.68 Rheumatoid Arthritis 99 95.36 Arthritis 46 87.88 INFLAMMATION 16 38.84 Hyperplasia 2 37.00 Apoptosis 2 6.08 Synovitis 21 5.00 Seronegative Spondarthritis 12 5.00 Necrosis 2 5.00 Crystal Associated Disease 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Blood monocytes may differentiate into DCs in the presence of GM-CSF, IL-4 and TNF-?

DCs Spec (may) Negative_regulation (differentiate) of Gene_expression (presence) of GM-CSF in monocytes

1) Confidence 0.03 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175027 Disease Relevance 0.87 Pain Relevance 0.56

General Comments

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