INT184370
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
In contrast, FcRn-/- offspring displayed significantly reduced OVA-specific IgG1 serum concentrations (< 6 ? | |||||||||||||||
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Maintaining autoantibody titers through FcRn-mediated recycling | |||||||||||||||
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The FcRn binds pinocytosed IgG only in the acidic environment of the endosome and releases intact IgG when its transport vesicle is redirected to the neutral pH of the cell surface. | |||||||||||||||
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General Comments
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