INT184370

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Context Info
Confidence 0.66
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.76
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Fcgrt)
Anatomy Link Frequency
vesicle 1
Fcgrt (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 62 97.92 Very High Very High Very High
rheumatoid arthritis 66 90.64 High High
Arthritis 80 85.84 High High
Inflammatory response 8 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 110 98.28 Very High Very High Very High
INFLAMMATION 67 97.92 Very High Very High Very High
Peritonitis 2 94.84 High High
Arthus Reaction 16 93.88 High High
Rheumatoid Arthritis 66 90.64 High High
Arthritis 84 85.84 High High
Hypergammaglobulinemia 2 81.28 Quite High
Hypersensitivity 65 76.88 Quite High
Autoimmune Disease 18 67.60 Quite High
Immunization 17 61.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, FcRn-/- offspring displayed significantly reduced OVA-specific IgG1 serum concentrations (< 6 ?
Localization (offspring) of FcRn
1) Confidence 0.66 Published 2010 Journal Clin Mol Allergy Section Body Doc Link PMC2914046 Disease Relevance 0.39 Pain Relevance 0
Maintaining autoantibody titers through FcRn-mediated recycling
Localization (recycling) of FcRn
2) Confidence 0.45 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175042 Disease Relevance 1.39 Pain Relevance 0.41
The FcRn binds pinocytosed IgG only in the acidic environment of the endosome and releases intact IgG when its transport vesicle is redirected to the neutral pH of the cell surface.
Localization (releases) of FcRn in vesicle
3) Confidence 0.45 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175042 Disease Relevance 0.98 Pain Relevance 0.22

General Comments

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