INT184384

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Context Info
Confidence 0.66
First Reported 2005
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 8
Total Number 12
Disease Relevance 5.45
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (DNAI1) cilium (DNAI1) cytoplasm (DNAI1)
Anatomy Link Frequency
T-cell 5
blood 1
macrophages 1
arms 1
DNAI1 (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 53 100.00 Very High Very High Very High
rheumatoid arthritis 33 100.00 Very High Very High Very High
cytokine 41 99.36 Very High Very High Very High
Arthritis 40 89.84 High High
Inflammation 91 84.08 Quite High
anesthesia 2 56.44 Quite High
Antihistamine 3 20.36 Low Low
headache 23 5.00 Very Low Very Low Very Low
Pain 9 5.00 Very Low Very Low Very Low
backache 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 33 100.00 Very High Very High Very High
Pulmonary Disease 111 99.92 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 577 99.52 Very High Very High Very High
Asthma 19 98.56 Very High Very High Very High
Arthritis 42 92.04 High High
Hypersensitivity 7 90.76 High High
Disease Progression 15 88.96 High High
Disease 52 88.92 High High
Pressure Volume 2 Under Development 26 85.60 High High
INFLAMMATION 93 84.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since then, the use of ICS has increased widely in urological surgeries, achieving considerable success in reducing ABT.[31617]
Gene_expression (use) of ICS
1) Confidence 0.66 Published 2010 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2938542 Disease Relevance 0.24 Pain Relevance 0.06
The next 15 patients formed the ICS group, and they received cell salvaged blood.
Gene_expression (group) of ICS in blood
2) Confidence 0.57 Published 2010 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2938542 Disease Relevance 0.27 Pain Relevance 0
ICS are widely used and prescribed in both adults and children, usually in long-term treatments.
Gene_expression (used) of ICS associated with corticosteroid
3) Confidence 0.33 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504079 Disease Relevance 0.71 Pain Relevance 0.34
ICS were not excluded, but the proportion of patients in each group on ICS as standard treatment is of the placebo group was not stated.
Neg (not) Gene_expression (excluded) of ICS associated with corticosteroid
4) Confidence 0.10 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2650606 Disease Relevance 0.45 Pain Relevance 0.10
The study, the longest of its kind, demonstrated no significant differences in lung function decline, exacerbation rates or deterioration in health status between patients in the treatment and placebo arms, except in the subgroup of patients not receiving ICS as standard management.
Neg (not) Gene_expression (receiving) of ICS in arms associated with corticosteroid
5) Confidence 0.10 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2650606 Disease Relevance 0.51 Pain Relevance 0.09
Among responders, median ELISpot response magnitudes were on the order of several hundred SFC/106 PBMC, and ICS detected CD4+ and CD8+ T-cell responses on the order of 0.1% to 1% of T cells.
Gene_expression (detected) of ICS in T-cell
6) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965084 Disease Relevance 0.35 Pain Relevance 0
Of these 26, two vaccine recipients had positive ICS responses in both T cell subsets at day 0, but both individuals showed responses to a larger number of antigens at day 28 (data not shown).
Gene_expression (responses) of ICS in T cell
7) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965084 Disease Relevance 0.07 Pain Relevance 0.03
By ICS analysis, both CD4+ and CD8+ T cell responses were detectable (representative high and low positive samples shown in Figure 4).
Gene_expression (analysis) of ICS in T cell
8) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965084 Disease Relevance 0.38 Pain Relevance 0.04
Of the 39 participants with detectable HIV-1-specific CD4+ T-cell responses to any PTE pool by ICS on day 28, 18 (46%) had responses detected in the IFN-?
Gene_expression (responses) of ICS in T-cell associated with acquired immune deficiency syndrome or hiv infection
9) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965084 Disease Relevance 0.37 Pain Relevance 0
In the ICS analyses, median percentages of T cells showing IFN-?
Gene_expression (analyses) of ICS in T cells
10) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965084 Disease Relevance 0.21 Pain Relevance 0
ICS was measured in 7 volunteers each of Groups C and D, and in 6 placebo recipients at only three visits; baseline, 2 weeks post DNA and 4 weeks post rAd5.
Gene_expression (measured) of ICS
11) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943475 Disease Relevance 0.42 Pain Relevance 0.05
and IL-1 production by human macrophages in RA after receptor ligation by small ICs has been shown recently.
Gene_expression (production) of ICs in macrophages associated with rheumatoid arthritis
12) Confidence 0.04 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175042 Disease Relevance 1.47 Pain Relevance 0.36

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