INT184410

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.11
First Reported 2005
Last Reported 2008
Negated 2
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 5.51
Pain Relevance 1.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

histone binding (ASF1A) nucleus (ASF1A)
Anatomy Link Frequency
CII 1
ASF1A (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 392 100.00 Very High Very High Very High
rheumatoid arthritis 150 99.82 Very High Very High Very High
tolerance 35 94.12 High High
imagery 6 93.60 High High
Inflammation 138 89.84 High High
Central nervous system 5 87.60 High High
antagonist 25 76.28 Quite High
alcohol 1 68.80 Quite High
cytokine 35 48.64 Quite Low
abdominal pain 1 13.24 Low Low
Disease Link Frequency Relevance Heat
Arthritis 452 100.00 Very High Very High Very High
Myositis 14 100.00 Very High Very High Very High
Rheumatoid Arthritis 150 99.82 Very High Very High Very High
Immunization 30 96.92 Very High Very High Very High
Disease 132 95.84 Very High Very High Very High
Multiple Sclerosis 65 92.88 High High
Encephalitis 5 90.12 High High
INFLAMMATION 114 89.84 High High
Lymphatic System Cancer 5 89.84 High High
Sprains And Strains 40 84.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Antinuclear antibodies were detected in low titer (1/80) with standard immunofluorescence, whereas the myositis-specific antibody anti-Jo-1 and the ENAs were negative.
Neg (negative) Gene_expression (negative) of myositis-specific antibody anti-Jo-1 associated with myositis
1) Confidence 0.11 Published 2008 Journal Cases J Section Body Doc Link PMC2584084 Disease Relevance 0.48 Pain Relevance 0.17
A gender bias as observed in humans for the risk of developing RA was not found for CIA in rhesus monkeys, although a prevalence in females has been found in the closely related cynomolgus macaque.


Neg (not) Gene_expression (found) of CIA associated with rheumatoid arthritis and arthritis
2) Confidence 0.08 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175046 Disease Relevance 1.00 Pain Relevance 0.36
This paradigm could explain why in monkeys that have recovered from CIA it is almost impossible to induce exacerbation of the arthritis by a second immunization with bovine collagen type II [26,51].
Gene_expression (recovered) of CIA associated with immunization and arthritis
3) Confidence 0.08 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175046 Disease Relevance 1.01 Pain Relevance 0.23
Furthermore, the Mamu-A26-associated CIA resistance was mainly observed in rhesus monkeys of Indian origin (B 't Hart, RE Bontrop, personal observation).
Gene_expression (resistance) of CIA associated with arthritis
4) Confidence 0.08 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175046 Disease Relevance 0.99 Pain Relevance 0.30
In the CIA model, CRP is elevated before macroscopic clinical signs are observed and can be used as an early marker for disease onset.
Gene_expression (model) of CIA associated with disease and arthritis
5) Confidence 0.08 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175046 Disease Relevance 1.17 Pain Relevance 0.49
The absence of anti-CII IgM production in CIA-resistant monkeys is highly suggestive of a causal link [27].
Gene_expression (production) of CIA in CII associated with arthritis
6) Confidence 0.08 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175046 Disease Relevance 0.87 Pain Relevance 0.39

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox