INT184458

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Context Info
Confidence 0.05
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.87
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Il17a, Adamts1) peptidase activity (Adamts1) extracellular space (Il17a)
proteinaceous extracellular matrix (Adamts1)
Anatomy Link Frequency
articular 2
Il17a (Mus musculus)
Adamts1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 4 96.00 Very High Very High Very High
cytokine 2 95.48 Very High Very High Very High
metalloproteinase 11 5.00 Very Low Very Low Very Low
Osteoarthritis 11 5.00 Very Low Very Low Very Low
Arthritis 8 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 2 97.48 Very High Very High Very High
Cancer 2 97.12 Very High Very High Very High
INFLAMMATION 3 96.00 Very High Very High Very High
Alzheimer's Dementia 1 87.20 High High
Adenocarcinoma 1 85.16 High High
Congenital Anomalies 4 77.60 Quite High
Growth Problems 1 75.24 Quite High
Syndrome 3 73.72 Quite High
Disease 2 42.60 Quite Low
Thrombotic Thrombocytopenic Purpura 2 42.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
in retinal pigment epithelium-derived cells [68] and ADAMTS-4 mRNA expression is increased by IL-17 in articular chondrocytes [69], indicating that other ADAMTS proteins might also be upregulated by inflammatory cytokines.
IL-17 Positive_regulation (increased) of Transcription (expression) of ADAMTS in articular associated with inflammation and cytokine
1) Confidence 0.05 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175049 Disease Relevance 0.87 Pain Relevance 0.18

General Comments

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