INT18446

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Context Info
Confidence 0.18
First Reported 1990
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.84
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Insr) endosome (Insr) plasma membrane (Insr)
nucleus (Insr)
Anatomy Link Frequency
liver 1
sympathetic 1
Insr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 5 100.00 Very High Very High Very High
substance P 5 100.00 Very High Very High Very High
tolerance 4 99.80 Very High Very High Very High
Catecholamine 2 86.08 High High
Neuropeptide 2 74.04 Quite High
Neurotransmitter 1 58.24 Quite High
Cholecystokinin 1 43.60 Quite Low
Enkephalin 1 41.36 Quite Low
Serotonin 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Impaired Glucose Tolerance 4 99.80 Very High Very High Very High
Reprotox - General 3 1 99.10 Very High Very High Very High
Obesity 85 97.00 Very High Very High Very High
Metabolic Syndrome 7 84.80 Quite High
Stress 15 83.52 Quite High
Increased Venous Pressure Under Development 2 79.96 Quite High
Diabetes Mellitus 7 78.88 Quite High
Cardiovascular Disease 2 73.72 Quite High
Coronary Heart Disease 1 48.32 Quite Low
Dyslipidemia /

Combined Dyslipidemia

2 45.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These multiple abnormalities were associated with significant changes in insulin sensitivity and IGT, marked changes in liver glucose metabolism, decreased pancreatic ?
Transcription (sensitivity) of insulin in liver associated with reprotox - general 3 and tolerance
1) Confidence 0.18 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2974659 Disease Relevance 0.84 Pain Relevance 0.05
In adult animals treated as neonates with the sympathetic neurotoxin 6-hydroxydopamine, a virtual absence of TH-IR and NPY-IR fibers was observed, whereas the distribution of CGRP-IR and SP-IR fibers appeared unaltered.
Transcription (distribution) of SP-IR in sympathetic associated with substance p and calcitonin gene-related peptide
2) Confidence 0.17 Published 1990 Journal Cell Tissue Res. Section Abstract Doc Link 1973633 Disease Relevance 0 Pain Relevance 0.57

General Comments

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