INT184460

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Context Info
Confidence 0.04
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.99
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Adamts1) extracellular region (Adamts1) proteinaceous extracellular matrix (Adamts1)
Il1 (Mus musculus)
Adamts1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 4 99.60 Very High Very High Very High
Inflammation 8 81.60 Quite High
metalloproteinase 22 5.00 Very Low Very Low Very Low
Osteoarthritis 22 5.00 Very Low Very Low Very Low
Arthritis 16 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 6 81.60 Quite High
Alzheimer's Dementia 2 79.68 Quite High
Necrosis 4 68.64 Quite High
Cancer 4 68.28 Quite High
Adenocarcinoma 2 56.32 Quite High
Congenital Anomalies 8 48.76 Quite Low
Growth Problems 2 46.40 Quite Low
Syndrome 6 44.88 Quite Low
Disease 4 13.76 Low Low
Thrombotic Thrombocytopenic Purpura 4 13.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
together with oncostatin M, but not either cytokine alone, upregulated ADAMTS-4 mRNA, whereas ADAMTS-5 mRNA was upregulated by IL-1?
IL-1 Positive_regulation (upregulated) of ADAMTS associated with cytokine
1) Confidence 0.04 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175049 Disease Relevance 0.49 Pain Relevance 0.20
together with oncostatin M, but not either cytokine alone, upregulated ADAMTS-4 mRNA, whereas ADAMTS-5 mRNA was upregulated by IL-1?
IL-1 Positive_regulation (upregulated) of ADAMTS associated with cytokine
2) Confidence 0.04 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1175049 Disease Relevance 0.50 Pain Relevance 0.20

General Comments

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