INT184479

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Context Info
Confidence 0.09
First Reported 2005
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 3.97
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Tfrc) peptidase activity (Tfrc) mitochondrion (Tfrc)
extracellular region (Tfrc) cytoplasmic membrane-bounded vesicle (Tfrc) plasma membrane (Tfrc)
Anatomy Link Frequency
mammary gland 1
liver 1
brain 1
spleen 1
Tfrc (Mus musculus)
Pain Link Frequency Relevance Heat
Multiple sclerosis 12 79.88 Quite High
Intracerebroventricular 16 74.64 Quite High
Inflammation 27 73.16 Quite High
cINOD 16 72.08 Quite High
Spinal cord 3 67.20 Quite High
anesthesia 1 65.28 Quite High
Central nervous system 10 62.96 Quite High
metalloproteinase 1 55.12 Quite High
Analgesic 6 37.76 Quite Low
Hippocampus 7 35.84 Quite Low
Disease Link Frequency Relevance Heat
Cancer 145 100.00 Very High Very High Very High
Targeted Disruption 9 98.08 Very High Very High Very High
Syndrome 3 91.36 High High
Retts Disease 3 90.40 High High
Disease 49 89.80 High High
Breast Cancer 42 87.64 High High
Neurological Disease 3 86.84 High High
Demyelinating Disease 12 79.88 Quite High
INFLAMMATION 37 73.16 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 29 65.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Homozygous APOE2, APOE3 and APOE4 targeted replacement (TR) mice 'humanized' at apoE were developed by Dr.
Regulation (targeted) of TR
1) Confidence 0.09 Published 2006 Journal J Neuroinflammation Section Body Doc Link PMC1584222 Disease Relevance 0 Pain Relevance 0.16
Recently, a transgenic mouse model was developed in which the human COX-2 gene was expressed in the mammary gland under the control of the murine mammary tumor virus promoter [15].
Regulation (control) of mammary tumor virus promoter in mammary gland associated with targeted disruption and cancer
2) Confidence 0.03 Published 2005 Journal Breast Cancer Res Section Body Doc Link PMC1175053 Disease Relevance 1.19 Pain Relevance 0.17
Some of the PEG molecules on the liposome surfaces were attached to a targeting monoclonal antibody anti-TFR, which targets the brain, liver, and spleen.
Regulation (targeting) of anti-TFR in liver
3) Confidence 0.00 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2673971 Disease Relevance 0.93 Pain Relevance 0.23
Some of the PEG molecules on the liposome surfaces were attached to a targeting monoclonal antibody anti-TFR, which targets the brain, liver, and spleen.
Regulation (targeting) of anti-TFR in brain
4) Confidence 0.00 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2673971 Disease Relevance 0.93 Pain Relevance 0.23
Some of the PEG molecules on the liposome surfaces were attached to a targeting monoclonal antibody anti-TFR, which targets the brain, liver, and spleen.
Regulation (targeting) of anti-TFR in spleen
5) Confidence 0.00 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2673971 Disease Relevance 0.93 Pain Relevance 0.23

General Comments

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