INT184529

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.49
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 7.06
Pain Relevance 1.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (SMUG1) hydrolase activity, acting on glycosyl bonds (SMUG1) nucleolus (SMUG1)
nucleus (SMUG1) DNA binding (SMUG1)
SMUG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
positron emission tomography 256 99.96 Very High Very High Very High
Inflammation 24 93.52 High High
imagery 362 92.28 High High
fibrosis 8 29.88 Quite Low
Dopamine 1 11.84 Low Low
Neurotransmitter 1 11.16 Low Low
isoflurane 15 5.00 Very Low Very Low Very Low
palliative 11 5.00 Very Low Very Low Very Low
Thoracotomy 8 5.00 Very Low Very Low Very Low
anesthesia 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 398 100.00 Very High Very High Very High
Granuloma 3 99.56 Very High Very High Very High
Metastasis 139 99.36 Very High Very High Very High
Lymphatic System Cancer 24 99.28 Very High Very High Very High
Breast Cancer 157 98.32 Very High Very High Very High
Disease 80 98.24 Very High Very High Very High
Stomach Cancer 9 98.20 Very High Very High Very High
Non-small-cell Lung Cancer 32 96.32 Very High Very High Very High
Esophageal Cancer 9 95.24 Very High Very High Very High
INFLAMMATION 26 93.52 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, FDG uptake reduction in patients with lymphoma can be monitored within a few hours after treatment [37,38].
Negative_regulation (reduction) of FDG associated with lymphatic system cancer
1) Confidence 0.49 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 0.93 Pain Relevance 0.13
Early decrease of FDG uptake has been monitored and seen in molecular targeted therapy (with imatinib) and radiotherapy as well [84].


Negative_regulation (decrease) of FDG
2) Confidence 0.36 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 0.99 Pain Relevance 0
Patients responding to treatment had a significant reduction of tumor FDG accumulation in relation to those not responding [20,41,43-45].
Negative_regulation (reduction) of FDG associated with cancer
3) Confidence 0.36 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 1.13 Pain Relevance 0
Performing these experiments in immunocompetent mice should be achievable since studies conducted in immunocompetent rats showed that treatment with a single dose of methylprednisolone resulted in decreased FDG uptake in granulomas [34].
Negative_regulation (decreased) of FDG associated with granuloma
4) Confidence 0.18 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2943464 Disease Relevance 0.82 Pain Relevance 0.19
For more information on the clinical effectiveness of PET, the interested reader is referred to the Health Technology Assessment (HTA) report conducted by Facey et al. [4], which gives a detailed overview of the clinical effectiveness of FDG-PET in various cancers.
Negative_regulation (effectiveness) of FDG associated with cancer and positron emission tomography
5) Confidence 0.18 Published 2010 Journal BMC Health Serv Res Section Body Doc Link PMC2959014 Disease Relevance 0.23 Pain Relevance 0.77
After one cycle of chemotherapy, a reduction of 18F-FDG had a high sensitivity for the prediction of a complete pathologic response [75].
Negative_regulation (reduction) of FDG
6) Confidence 0.07 Published 2005 Journal Breast Cancer Res Section Body Doc Link PMC1175073 Disease Relevance 0.94 Pain Relevance 0.09
However, like SMM, 18F-FDG is limited by a lower sensitivity in detecting some breast tumors because of their small size, metabolic activity, histological subtype, microscopic tumor growth pattern and proliferation [39].
Negative_regulation (limited) of FDG associated with cancer and breast cancer
7) Confidence 0.05 Published 2005 Journal Breast Cancer Res Section Body Doc Link PMC1175073 Disease Relevance 1.29 Pain Relevance 0.12
In contrast, the decrease in 18F-FDG tumor uptake upon carbogen breathing in small regions of the tumor in the present study was up to 21%, suggesting that in these small regions tumor glucose metabolism is altered as a result of increased perfusion and oxygenation.
Negative_regulation (decrease) of FDG associated with cancer
8) Confidence 0.03 Published 2006 Journal Radiat Oncol Section Body Doc Link PMC1436004 Disease Relevance 0.72 Pain Relevance 0.16

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox