INT184530

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Context Info
Confidence 0.52
First Reported 2005
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.54
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (SMUG1) hydrolase activity, acting on glycosyl bonds (SMUG1) nucleolus (SMUG1)
nucleus (SMUG1) DNA binding (SMUG1)
Anatomy Link Frequency
axillary 1
superior 1
SMUG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 166 99.96 Very High Very High Very High
Inflammation 17 57.64 Quite High
positron emission tomography 24 38.68 Quite Low
fibrosis 5 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
opiate 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 231 99.90 Very High Very High Very High
Metastasis 75 99.60 Very High Very High Very High
Lobular Carcinoma 8 98.44 Very High Very High Very High
Breast Cancer 141 97.44 Very High Very High Very High
Ductal Carcinoma 2 96.80 Very High Very High Very High
Fibroadenoma 2 90.96 High High
Disease 40 86.84 High High
Head & Neck Cancer 7 83.68 Quite High
Carcinoma 6 70.92 Quite High
Squamous Cell Carcinoma 2 65.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, the histological characteristics of the tumor may affect FDG-PET imaging enough to fail to visualize the primary tumor [22].
Spec (may) Regulation (affect) of FDG-PET associated with cancer and imagery
1) Confidence 0.52 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 1.19 Pain Relevance 0.05
From FDG studies, it is known that, in general, changes in FDG signal appear before changes can be detected in tumor volume [34].
Regulation (changes) of FDG associated with cancer
2) Confidence 0.27 Published 2007 Journal Mol Imaging Biol Section Body Doc Link PMC2040178 Disease Relevance 0.75 Pain Relevance 0
A recent prospective multicenter study conducted on 360 women with newly diagnosed invasive breast cancer reported values of 61%, 80%, 62% and 79% for sensitivity, specificity and positive and negative predictive values, respectively [61]. 18F-FDG-PET was less sensitive in detecting axillary metastases from lobular carcinoma (sensitivity 25%) than ductal carcinoma (sensitivity 66%).
Regulation (sensitive) of FDG in axillary associated with ductal carcinoma, breast cancer, lobular carcinoma and metastasis
3) Confidence 0.03 Published 2005 Journal Breast Cancer Res Section Body Doc Link PMC1175073 Disease Relevance 0.85 Pain Relevance 0.03
For the detection of lymph node metastases of the axilla, 18F-FDG was more sensitive than planar SMM (sensitivity 36 to 84%, specificity 86 to 100% [19-21]) and SPECT SMM, in which sensitivity in some studies seemed to be superior to that of planar imaging (sensitivity 37.5 to 84.2%, specificity 91% [19,22]).
Regulation (sensitive) of FDG in superior associated with imagery and metastasis
4) Confidence 0.03 Published 2005 Journal Breast Cancer Res Section Body Doc Link PMC1175073 Disease Relevance 0.74 Pain Relevance 0.08

General Comments

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