INT184537

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Context Info
Confidence 0.34
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.37
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ccl2, Spp1) extracellular region (Ccl2, Spp1) cytoplasm (Ccl2, Spp1)
cell differentiation (Spp1) aging (Ccl2) cell adhesion (Spp1)
Anatomy Link Frequency
macrophage 1
Ccl2 (Rattus norvegicus)
Spp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 13 98.78 Very High Very High Very High
chemokine 7 74.40 Quite High
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Renal Disease 1 99.82 Very High Very High Very High
Diabetes Mellitus 58 99.54 Very High Very High Very High
Hypertension 52 99.28 Very High Very High Very High
INFLAMMATION 13 98.78 Very High Very High Very High
Adhesions 3 96.50 Very High Very High Very High
Disease 6 77.08 Quite High
Polyuria 1 45.56 Quite Low
Body Weight 5 41.20 Quite Low
Hypertrophy 1 32.16 Quite Low
Albuminuria 1 28.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Expression of mediators regulating macrophage infiltration (MCP-1, osteopontin, RANTES) and adhesion molecules involved in macrophage infiltration (ICAM-1, VCAM-1) was investigated to further elucidate inflammatory pathways in hypertensive and diabetic renal disease: In TGR rats, renal MCP-1 and osteopontin mRNA steady state levels were increased compared to SD controls, as determined by real-time RT-PCR (figure 3A and 3B).
MCP-1 Positive_regulation (rats) of osteopontin in macrophage associated with inflammation, diabetes mellitus, renal disease, hypertension and adhesions
1) Confidence 0.34 Published 2005 Journal BMC Nephrol Section Body Doc Link PMC1175090 Disease Relevance 1.37 Pain Relevance 0.09

General Comments

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