INT184559

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Context Info
Confidence 0.12
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.74
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitosis (Aurka) cytoskeleton (Aurka) nucleus (Aurka)
cell cycle (Aurka) cell division (Aurka) cytoplasm (Aurka)
Aurka (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chronic Renal Failure 30 99.72 Very High Very High Very High
Myocardial Infarction 7 78.80 Quite High
Death 9 77.40 Quite High
Renal Failure 1 75.16 Quite High
Stress 2 71.64 Quite High
Disorder Of Lipid Metabolism 23 68.64 Quite High
Targeted Disruption 12 62.52 Quite High
Increased Venous Pressure Under Development 5 45.44 Quite Low
Cardiovascular Disease 5 38.36 Quite Low
Disease 2 26.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Upstream signaling pathways involved in the blockage of G2/M transition included lack of persistent Erk1/2 activation and inability to up-regulate the levels of Cdk1, Plk1, Aurora A and B, and Mad2 along with a defective histone 3 phosphorylation and lack of chromatin condensation.
Regulation (regulate) of Aurora A
1) Confidence 0.12 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2940888 Disease Relevance 0.13 Pain Relevance 0
AURORA is the first international, prospective, randomised, double-blind, placebo-controlled study to assess whether statin therapy alone can reduce the incidence of coronary events in ESRD patients on chronic haemodialysis.
Regulation (controlled) of AURORA associated with chronic renal failure
2) Confidence 0.06 Published 2005 Journal Curr Control Trials Cardiovasc Med Section Body Doc Link PMC1175096 Disease Relevance 0.61 Pain Relevance 0

General Comments

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