INT184605

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Context Info
Confidence 0.19
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.39
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (APC) chromosome organization (APC) cell adhesion (APC)
plasma membrane (APC) cytoskeleton (APC) nucleus (APC)
Anatomy Link Frequency
endothelial cell 2
APC (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 20 93.32 High High
cytokine 9 89.36 High High
Inflammatory response 5 85.64 High High
aspirin 7 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 3 99.84 Very High Very High Very High
Carcinoma 1 98.88 Very High Very High Very High
Apoptosis 7 96.72 Very High Very High Very High
Sepsis 7 95.72 Very High Very High Very High
Pressure And Volume Under Development 5 95.44 Very High Very High Very High
Necrosis 16 93.84 High High
INFLAMMATION 26 93.32 High High
Pancreatitis 25 90.72 High High
Malignant Neoplastic Disease 1 89.60 High High
Anaplastic Astrocytoma 1 88.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Binding of APC to the endothelial cell protein C receptor results in a number of actions, including increased activity of APC itself and inhibition of both NF-?
Positive_regulation (increased) of Transcription (activity) of APC in endothelial cell
1) Confidence 0.19 Published 2005 Journal Crit Care Section Body Doc Link PMC1175873 Disease Relevance 1.85 Pain Relevance 0.33
Specifically, the mutation of APC is a leading cause of colorectal carcinomas [16], and the relative mRNA and protein expression of ?
Positive_regulation (cause) of Transcription (mutation) of APC associated with colon cancer
2) Confidence 0.11 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2955614 Disease Relevance 0.54 Pain Relevance 0

General Comments

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