INT184716

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Context Info
Confidence 0.34
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.91
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Smad7) plasma membrane (Smad7) nucleus (Smad7)
intracellular (Smad7) protein complex (Smad7) cytoplasm (Smad7)
Smad7 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 12 99.52 Very High Very High Very High
antagonist 1 99.24 Very High Very High Very High
metalloproteinase 1 83.12 Quite High
Inflammation 25 51.08 Quite High
cytokine 8 47.16 Quite Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
wide dynamic range 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosis 9 99.52 Very High Very High Very High
Lung Injury 11 93.80 High High
Pulmonary Fibrosis 8 92.40 High High
Targeted Disruption 40 83.20 Quite High
Soft Tissue Injuries 1 78.24 Quite High
Injury 12 62.64 Quite High
Disease 1 60.72 Quite High
INFLAMMATION 31 51.08 Quite High
Necrosis 1 43.28 Quite Low
Cancer 1 42.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In cardiac myofibroblasts, ectopic Smad7 protein is associated with accelerated activation of pro-MMP-2 into MMP-2 [25].
Smad7 Binding (associated) of
1) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2993968 Disease Relevance 0.06 Pain Relevance 0.04
Recently, Smad7, an intracellular antagonist of TGF?
Smad7 Binding (Recently) of associated with antagonist
2) Confidence 0.25 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1177930 Disease Relevance 0.85 Pain Relevance 0.25

General Comments

This test has worked.

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