INT184729

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Context Info
Confidence 0.67
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.10
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (COL2A1) extracellular region (COL2A1) cytoplasm (COL2A1)
COL2A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Earache 1 25.56 Quite Low
Osteoarthritis 29 5.00 Very Low Very Low Very Low
Pain 13 5.00 Very Low Very Low Very Low
Analgesic 5 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Otitis Media 85 100.00 Very High Very High Very High
Suppurative Otitis Media 5 98.24 Very High Very High Very High
Sprains And Strains 2 87.60 High High
Infection 10 85.28 High High
Death 3 67.60 Quite High
Apoptosis 3 49.92 Quite Low
Stress 8 45.80 Quite Low
Osteoporosis 14 25.56 Quite Low
Earache 1 25.56 Quite Low
Fever 22 25.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, while high NaCl rapidly activates p38 MAPK, its action can be isoform specific and may exert opposing effects on NFAT5 [85], which in turn may influence COL2A1 and AGC1 transcription differently in a tonicity-dependent manner.
Transcription (transcription) of COL2A1
1) Confidence 0.67 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911888 Disease Relevance 0.07 Pain Relevance 0
For high-risk populations, we believe our description of "persistent AOM" is likely to be generalisable.
Transcription (description) of AOM associated with otitis media
2) Confidence 0.60 Published 2005 Journal BMC Pediatr Section Body Doc Link PMC1177962 Disease Relevance 0.84 Pain Relevance 0
The case study pertains to the routine prescription of antibiotics for acute otitis media (AOM) in children.
Transcription (prescription) of AOM associated with otitis media
3) Confidence 0.36 Published 2009 Journal Trials Section Body Doc Link PMC2636799 Disease Relevance 0.20 Pain Relevance 0
Col2a1 transcription was down-regulated in intermediate while up-regulated in the fused group (n.s.).
Transcription (transcription) of Col2a1
4) Confidence 0.21 Published 2010 Journal BMC Physiol Section Body Doc Link PMC2909226 Disease Relevance 0 Pain Relevance 0

General Comments

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