INT184748

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Context Info
Confidence 0.32
First Reported 2005
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.75
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Gem) plasma membrane (Gem) GTPase activity (Gem)
Gem (Mus musculus)
Pain Link Frequency Relevance Heat
palliative 4 89.40 High High
Inflammation 3 59.72 Quite High
Bile 1 32.24 Quite Low
imagery 3 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Thoracotomy 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Antiemetics 1 5.00 Very Low Very Low Very Low
Versed 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lung Cancer 10 99.76 Very High Very High Very High
Cancer 59 99.00 Very High Very High Very High
Carcinoma 17 91.68 High High
Apoptosis 60 87.60 High High
Non-small-cell Lung Cancer 16 86.56 High High
Disease 19 84.20 Quite High
Death 15 72.80 Quite High
Hepatitis 1 65.36 Quite High
Infection 2 64.92 Quite High
Inflammatory Bowel Disease 2 61.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GEM enters the cells via a nucleoside transport system and is subsequently phosphorylated to inhibit ribonucleotide reductase (RNR) and to compete with dCTP for incorporation into DNA [7].
Phosphorylation (phosphorylated) of GEM
1) Confidence 0.32 Published 2006 Journal J Carcinog Section Body Doc Link PMC1665446 Disease Relevance 0.85 Pain Relevance 0.08
Gemcitabine is phosphorylated by deoxycytidine kinase into the active metabolite gemcitabine triphosphate (GemTP).
Phosphorylation (phosphorylated) of GemTP
2) Confidence 0.07 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1180427 Disease Relevance 0.90 Pain Relevance 0.12

General Comments

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