INT18483

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Context Info
Confidence 0.97
First Reported 1990
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.58
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Tyr) cell proliferation (Tyr) oxidoreductase activity (Tyr)
cytoplasm (Tyr)
Anatomy Link Frequency
RBCs 1
Tyr (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 5 99.92 Very High Very High Very High
aspirin 4 75.00 Quite High
Dynorphin 1 69.84 Quite High
Analgesic 1 54.88 Quite High
Disease Link Frequency Relevance Heat
Skin Cancer 2 78.44 Quite High
Experimental Melanoma 2 75.00 Quite High
Cancer 1 61.76 Quite High
Stroke 1 59.96 Quite High
Myocardial Infarction 1 59.64 Quite High
Autolysis 2 52.24 Quite High
Pigment Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, the depigmenting effect of ASA might be due to inhibition of tyrosinase expression or enhancement of tyrosinase degradation.
Protein_catabolism (degradation) of tyrosinase
1) Confidence 0.97 Published 2008 Journal Biol. Pharm. Bull. Section Abstract Doc Link 18175938 Disease Relevance 0.48 Pain Relevance 0.15
These findings show that RBCs can take up, store, and degrade Tyr-Pro containing peptides.
Protein_catabolism (degrade) of Tyr-Pro in RBCs
2) Confidence 0.05 Published 1990 Journal Biochem. Pharmacol. Section Abstract Doc Link 1974425 Disease Relevance 0 Pain Relevance 0.10
Tyr-Gly-Gly-Phe-Leu was degraded by DPPI into Tyr-Gly and Gly-Phe-Leu with no further degradation of the newly generated tripeptide.
Protein_catabolism (degraded) of Tyr-Gly
3) Confidence 0.00 Published 1993 Journal Neurochem. Int. Section Abstract Doc Link 8443565 Disease Relevance 0.05 Pain Relevance 0.17
Tyr-Gly-Gly-Phe-Leu was degraded by DPPI into Tyr-Gly and Gly-Phe-Leu with no further degradation of the newly generated tripeptide.
Neg (no) Protein_catabolism (degradation) of Tyr-Gly
4) Confidence 0.00 Published 1993 Journal Neurochem. Int. Section Abstract Doc Link 8443565 Disease Relevance 0.05 Pain Relevance 0.17

General Comments

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