INT184848

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Context Info
Confidence 0.26
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.93
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Drd1a) endoplasmic reticulum (Drd1a) plasma membrane (Drd1a)
nucleus (Drd1a) intracellular (Drd1a) signal transducer activity (Drd1a)
Anatomy Link Frequency
striatum 2
Drd1a (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 152 98.08 Very High Very High Very High
Substantia nigra 7 95.28 Very High Very High Very High
midbrain 21 94.44 High High
Serotonin 22 88.28 High High
monoamine 5 87.28 High High
antagonist 9 59.80 Quite High
Neurotransmitter 8 53.60 Quite High
agonist 8 35.80 Quite Low
addiction 1 29.92 Quite Low
Glutamate 20 27.76 Quite Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 1 86.96 High High
Cognitive Disorder 9 77.04 Quite High
Hypoxia 4 73.28 Quite High
Attention Deficit Hyperactivity Disorder 163 72.40 Quite High
Drug Dependence 1 30.32 Quite Low
Ocular Toxicity (including Many Sub-types) 11 5.00 Very Low Very Low Very Low
Hypertension 7 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, DRD1 and DRD2 mRNA levels were increased in the striatum suggesting impaired release of dopamine [185].
Positive_regulation (increased) of Transcription (levels) of DRD1 in striatum associated with dopamine
1) Confidence 0.26 Published 2005 Journal Behav Brain Funct Section Body Doc Link PMC1180819 Disease Relevance 0.93 Pain Relevance 0.65

General Comments

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