INT184853

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Context Info
Confidence 0.65
First Reported 2005
Last Reported 2010
Negated 3
Speculated 0
Reported most in Body
Documents 87
Total Number 90
Disease Relevance 89.20
Pain Relevance 11.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
impression 3
capsule 2
brain 1
CSF 1
striatum 1
ADHD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 398 100.00 Very High Very High Very High
Somatosensory cortex 385 100.00 Very High Very High Very High
Dopamine 2231 98.94 Very High Very High Very High
imagery 127 98.80 Very High Very High Very High
addiction 195 98.60 Very High Very High Very High
Catecholamine 27 98.60 Very High Very High Very High
behavioral therapy 290 98.16 Very High Very High Very High
tolerance 57 98.12 Very High Very High Very High
alcohol 305 97.88 Very High Very High Very High
Neurotransmitter 470 97.36 Very High Very High Very High
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 13989 100.00 Very High Very High Very High
Manic Depressive Disorder 921 100.00 Very High Very High Very High
Syndrome 498 100.00 Very High Very High Very High
Depression 467 100.00 Very High Very High Very High
Attention Deficit And Disruptive Behavior Disorders 296 100.00 Very High Very High Very High
Autism 93 100.00 Very High Very High Very High
Anxiety Disorder 528 99.92 Very High Very High Very High
Hypertension 119 99.80 Very High Very High Very High
Toxicity 16 99.80 Very High Very High Very High
Drug Dependence 546 99.28 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Three subtypes of ADHD are recognized: ADHD predominantly inattentive type (ADHD-I), ADHD predominantly hyperactive–impulsive type (ADHD-H) and ADHD combined type (ADHD-C; both inattentive and hyperactive–impulsive symptoms), with the ADHD-I subtype being the most common diagnosis in adults.1,5
Gene_expression (type) of ADHD associated with attention deficit hyperactivity disorder
1) Confidence 0.65 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2697545 Disease Relevance 1.68 Pain Relevance 0
As discussed, the expression of ADHD in adults is to some extent different from that in children and the diagnostic descriptions of some of the features need to be adapted to adult expressions of the disorder.
Gene_expression (expression) of ADHD associated with attention deficit hyperactivity disorder
2) Confidence 0.58 Published 2010 Journal BMC Psychiatry Section Body Doc Link PMC2942810 Disease Relevance 1.00 Pain Relevance 0
Further, although it appears that the ADHD symptoms in those with both ADHD and PBD did not improve as much as those with ADHD-only (55% versus 76% if one takes 30% reduction as a good indicator of improvement in ADHD symptoms [44]), the ADHD-only sample showed a higher baseline value; the LOCF values were comparable.
Gene_expression (symptoms) of ADHD associated with manic depressive disorder and attention deficit hyperactivity disorder
3) Confidence 0.58 Published 2010 Journal BMC Psychiatry Section Body Doc Link PMC2954995 Disease Relevance 1.78 Pain Relevance 0.05
Three subtypes of ADHD are recognized: ADHD predominantly inattentive type (ADHD-I), ADHD predominantly hyperactive–impulsive type (ADHD-H) and ADHD combined type (ADHD-C; both inattentive and hyperactive–impulsive symptoms), with the ADHD-I subtype being the most common diagnosis in adults.1,5
Gene_expression (type) of ADHD associated with attention deficit hyperactivity disorder
4) Confidence 0.57 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2697545 Disease Relevance 1.67 Pain Relevance 0
The increasing amount of evidence regarding the impact of the persistent symptoms of ADHD from childhood into adulthood on critical areas of functioning, including education, employment, relationships with family and peers, and the development of comorbid conditions such as disorders of anxiety, depressive spectrum, and SUD, have led to better recognition of ADHD worldwide and even, in some instances, to the development of new treatment guidelines.88
Gene_expression (worldwide) of ADHD associated with drug dependence, depression, anxiety disorder and attention deficit hyperactivity disorder
5) Confidence 0.57 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2697545 Disease Relevance 1.15 Pain Relevance 0.10
Three subtypes of ADHD are recognized: ADHD predominantly inattentive type (ADHD-I), ADHD predominantly hyperactive–impulsive type (ADHD-H) and ADHD combined type (ADHD-C; both inattentive and hyperactive–impulsive symptoms), with the ADHD-I subtype being the most common diagnosis in adults.1,5
Gene_expression (type) of ADHD associated with attention deficit hyperactivity disorder
6) Confidence 0.57 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2697545 Disease Relevance 1.66 Pain Relevance 0
According to the most recent analysis of US prescribing patterns, the long-acting agents account for 78% of ADHD prescriptions in the pediatric population (patients prior to 17 years of age), but only for 49% of adult ADHD prescriptions, in spite of the fact that adults may have even greater difficulties with medication compliance and issues related to drug abuse and diversion than those of younger age patients.32 A number of studies have examined the patterns of compliance in adults with ADHD.
Gene_expression (prescriptions) of ADHD associated with drug abuse and attention deficit hyperactivity disorder
7) Confidence 0.57 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2697545 Disease Relevance 0.83 Pain Relevance 0.14
Three subtypes of ADHD are recognized: ADHD predominantly inattentive type (ADHD-I), ADHD predominantly hyperactive–impulsive type (ADHD-H) and ADHD combined type (ADHD-C; both inattentive and hyperactive–impulsive symptoms), with the ADHD-I subtype being the most common diagnosis in adults.1,5
Gene_expression (type) of ADHD associated with attention deficit hyperactivity disorder
8) Confidence 0.57 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2697545 Disease Relevance 1.75 Pain Relevance 0
In addition to the results indicating a differential response between the two treatments (OROS-MPH is more effective in decreasing symptoms of ADHD than ATX), there was also some evidence for preferential response, with one-third of the patients responding to either OROS-MPH or ATX, but not both.
Gene_expression (effective) of ADHD associated with attention deficit hyperactivity disorder
9) Confidence 0.57 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2697545 Disease Relevance 0.46 Pain Relevance 0
The results indicated that all 3 doses produced larger changes in ADHD-RS scores than placebo (placebo = ?
Gene_expression (scores) of ADHD-RS associated with attention deficit hyperactivity disorder
10) Confidence 0.57 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2697545 Disease Relevance 0.72 Pain Relevance 0.09
The notion that ADHD is a disorder of childhood and affected children “grow out” of ADHD during puberty (Okie 2006) was common until the 1990s (Barkley 2006a).
Gene_expression (grow) of ADHD associated with attention deficit hyperactivity disorder
11) Confidence 0.56 Published 2010 Journal Atten Defic Hyperact Disord Section Body Doc Link PMC3000907 Disease Relevance 0.86 Pain Relevance 0
Drug holidays: a way of controlling adverse effects of ADHD drugs?
Gene_expression (drugs) of ADHD associated with attention deficit hyperactivity disorder
12) Confidence 0.55 Published 2010 Journal Eur Child Adolesc Psychiatry Section Body Doc Link PMC3012210 Disease Relevance 1.90 Pain Relevance 0
A flow chart for both the ADHD specialist and hypertension specialist is attached (Fig. 1).Fig. 1Recommendation for blood pressure (BP) monitoring and management in ADHD patients
Gene_expression (specialist) of ADHD in blood associated with hypertension and attention deficit hyperactivity disorder
13) Confidence 0.55 Published 2010 Journal Eur Child Adolesc Psychiatry Section Body Doc Link PMC3012210 Disease Relevance 1.02 Pain Relevance 0
The FDA also reviewed industry post-marketing surveillance case reports in the United States for ADHD drugs prescribed in children and adults between 2000 and 2005 and found 865 reports of psychosis events [144].
Gene_expression (drugs) of ADHD associated with psychosis and attention deficit hyperactivity disorder
14) Confidence 0.55 Published 2010 Journal Eur Child Adolesc Psychiatry Section Body Doc Link PMC3012210 Disease Relevance 1.64 Pain Relevance 0
Systematic review has indicated that there is a relationship between the presence of ADHD itself and suicidal attempts [161]; so it should not automatically be assumed that any suicidal thinking or attempt is an adverse effect of medication.
Gene_expression (presence) of ADHD associated with attention deficit hyperactivity disorder
15) Confidence 0.55 Published 2010 Journal Eur Child Adolesc Psychiatry Section Body Doc Link PMC3012210 Disease Relevance 1.10 Pain Relevance 0
The difference is that since the levels of hyperactivity and inattention are much higher in ADHD subjects, the improvement is relatively much greater, giving the impression that they respond while non-ADHD subjects do not.
Gene_expression (subjects) of ADHD in impression associated with attention deficit hyperactivity disorder
16) Confidence 0.54 Published 2005 Journal Theor Biol Med Model Section Body Doc Link PMC1352384 Disease Relevance 1.18 Pain Relevance 0.27
Heavy metal toxicity: Role in autism and ADHD
Gene_expression (autism) of ADHD associated with toxicity, autism and attention deficit hyperactivity disorder
17) Confidence 0.54 Published 2005 Journal Theor Biol Med Model Section Body Doc Link PMC1352384 Disease Relevance 0.73 Pain Relevance 0.04
ADHD and many other complex disorders represent the upper end of a continuum of severity
Gene_expression (represent) of ADHD in upper end associated with attention deficit hyperactivity disorder
18) Confidence 0.54 Published 2005 Journal Theor Biol Med Model Section Body Doc Link PMC1352384 Disease Relevance 1.43 Pain Relevance 0.12
How is ADHD diagnosed?
Gene_expression (diagnosed) of ADHD associated with attention deficit hyperactivity disorder
19) Confidence 0.54 Published 2005 Journal Theor Biol Med Model Section Body Doc Link PMC1352384 Disease Relevance 1.15 Pain Relevance 0
Clinical aspects of ADHD
Gene_expression (aspects) of ADHD associated with attention deficit hyperactivity disorder
20) Confidence 0.54 Published 2005 Journal Theor Biol Med Model Section Body Doc Link PMC1352384 Disease Relevance 0.89 Pain Relevance 0

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