INT184952

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Context Info
Confidence 0.12
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (NLRP1) extracellular matrix organization (MMP9) enzyme binding (NLRP1)
protein complex (MMP9) cytoplasm (NLRP1) cytosol (NLRP1)
Anatomy Link Frequency
reservoirs 2
NLRP1 (Homo sapiens)
MMP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 2 35.88 Quite Low
withdrawal 2 12.28 Low Low
psoriasis 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 23 92.96 High High
Metastasis 2 87.68 High High
Breast Cancer 2 75.76 Quite High
Apoptosis 8 5.00 Very Low Very Low Very Low
Colon Cancer 8 5.00 Very Low Very Low Very Low
Psoriasis 5 5.00 Very Low Very Low Very Low
Skin Cancer 4 5.00 Very Low Very Low Very Low
Repression 3 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NAC has been proposed to inhibit activation of latent MMP9 protein in ECM reservoirs by removal of its propeptide and by competing for the zink ion which is necessary for enzymatic function [43].
NAC Negative_regulation (inhibit) of Positive_regulation (activation) of MMP9 in reservoirs
1) Confidence 0.12 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1182358 Disease Relevance 0.34 Pain Relevance 0

General Comments

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