INT184956

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Context Info
Confidence 0.42
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (ID1, CDKN2A) nucleus (ID1, CDKN2A) nucleoplasm (CDKN2A)
DNA binding (CDKN2A) protein complex (CDKN2A) cytosol (CDKN2A)
ID1 (Homo sapiens)
CDKN2A (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 5.12 Low Low
psoriasis 3 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Psoriasis 5 87.84 High High
Aging 1 64.88 Quite High
Ovarian Cancer 1 61.68 Quite High
Cancer 23 50.00 Quite Low
INFLAMMATION 2 5.12 Low Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Colon Cancer 8 5.00 Very Low Very Low Very Low
Skin Cancer 4 5.00 Very Low Very Low Very Low
Repression 3 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous reports have also shown that ID-1 is a negative transcriptional regulator of CDKN2A (p16/p14/p19), which induces G1 arrest through the inhibition of Rb phosphorylation by cdk -4 and -6 [15].
ID-1 Negative_regulation (regulator) of CDKN2A
1) Confidence 0.42 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1182358 Disease Relevance 0.21 Pain Relevance 0

General Comments

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