INT18499

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Context Info
Confidence 0.12
First Reported 1990
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (SUMO1) nucleus (SUMO1) cytoplasm (SUMO1)
Anatomy Link Frequency
platelet 2
SUMO1 (Homo sapiens)
SEC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 8 83.04 Quite High
antagonist 2 75.12 Quite High
Clonidine 2 52.24 Quite High
Serotonin 2 41.04 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The binding properties of p-[125I]iodoclonidine [( 125I]PIC) to human platelet membranes and the functional characteristics of PIC are reported. [125I]PIC bound rapidly and reversibly to platelet membranes, with a first-order association rate constant (kon) at room temperature of 8.0 +/- 2.7 x 10(6) M-1 sec-1 and a dissociation rate constant (koff) of 2.0 +/- 0.8 x 10(-3) sec-1.
PIC Binding (bound) of sec-1 in platelet
1) Confidence 0.12 Published 1990 Journal Mol. Pharmacol. Section Abstract Doc Link 1974694 Disease Relevance 0 Pain Relevance 0.11
The binding properties of p-[125I]iodoclonidine [( 125I]PIC) to human platelet membranes and the functional characteristics of PIC are reported. [125I]PIC bound rapidly and reversibly to platelet membranes, with a first-order association rate constant (kon) at room temperature of 8.0 +/- 2.7 x 10(6) M-1 sec-1 and a dissociation rate constant (koff) of 2.0 +/- 0.8 x 10(-3) sec-1.
PIC Binding (bound) of sec-1 in platelet
2) Confidence 0.12 Published 1990 Journal Mol. Pharmacol. Section Abstract Doc Link 1974694 Disease Relevance 0 Pain Relevance 0.17

General Comments

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