INT185009

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Context Info
Confidence 0.56
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.04
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (BMP4) growth (BMP4) extracellular region (BMP4)
proteinaceous extracellular matrix (BMP4)
BMP4 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 3 98.28 Very High Very High Very High
cINOD 4 66.24 Quite High
Spinal cord 6 51.92 Quite High
psoriasis 3 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Intractable pain 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrodysplasia Ossificans Progressiva 1 90.00 High High
Recurrence 3 89.20 High High
Heterotopic Ossification 39 88.08 High High
Colorectal Cancer 1 75.56 Quite High
Disease 2 70.64 Quite High
INFLAMMATION 3 65.84 Quite High
Osteoporosis 1 62.08 Quite High
Cancer 23 56.32 Quite High
Syndrome 1 54.72 Quite High
Spinal Cord Injury 5 51.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is postulated that the BMP-4 gene itself may not be defective but a defect in the genes that code BMP-4 antagonists leads to suppression of inhibitory mechanisms and overexpression of BMP-4 [24].
Negative_regulation (defective) of BMP-4 associated with antagonist
1) Confidence 0.56 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2908060 Disease Relevance 0.91 Pain Relevance 0.25
family member BMP-4 was repressed.
Negative_regulation (repressed) of BMP-4
2) Confidence 0.26 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1182358 Disease Relevance 0.13 Pain Relevance 0

General Comments

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