INT185014

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Context Info
Confidence 0.43
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.56
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP9) extracellular space (MMP9) extracellular region (MMP9)
proteinaceous extracellular matrix (MMP9) extracellular matrix organization (MMP9) protein complex (MMP9)
MMP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 57.04 Quite High
Inflammation 5 56.32 Quite High
Arthritis 4 54.64 Quite High
metalloproteinase 64 50.00 Quite Low
cytokine 4 5.00 Very Low Very Low Very Low
psoriasis 3 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosarcoma 3 86.72 High High
Cancer 33 83.68 Quite High
Metastasis 5 78.40 Quite High
Breast Cancer 2 66.48 Quite High
Arthralgia 1 57.52 Quite High
INFLAMMATION 5 56.32 Quite High
Arthritis 4 54.64 Quite High
Colon Cancer 9 5.00 Very Low Very Low Very Low
Apoptosis 9 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hence, our data may imply that post-transcriptional regulation of MMP9 prevails over the transcriptional changes as the major control mechanism.
Regulation (regulation) of Transcription (transcriptional) of MMP9
1) Confidence 0.43 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1182358 Disease Relevance 0.31 Pain Relevance 0
Transfection studies carried out with MMP-9 and AP-1 reporter constructs suggested that the observed reduction in MMP-9 expression was due to down-regulation of MMP-9 transcription which mediated via inhibition of AP-1.
Regulation (regulation) of Transcription (transcription) of MMP-9
2) Confidence 0.21 Published 2009 Journal Marine Drugs Section Body Doc Link PMC2707034 Disease Relevance 0.26 Pain Relevance 0.11

General Comments

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