INT185030

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Context Info
Confidence 0.35
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.60
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CDKN2B) nucleus (CDKN2B) kinase activity (CDKN2B)
cytoplasm (CDKN2B)
CDKN2B (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 73.64 Quite High
Inflammation 11 15.44 Low Low
psoriasis 6 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
Angina 4 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 62 98.92 Very High Very High Very High
Coronary Artery Disease 38 98.64 Very High Very High Very High
Disorder Of Lipid Metabolism 1 91.68 High High
Cancer 48 86.16 High High
Disease 8 84.80 Quite High
Apoptosis 18 80.16 Quite High
Targeted Disruption 2 69.92 Quite High
Repression 6 68.56 Quite High
Cardiovascular Disease 1 63.60 Quite High
Leukemia 2 63.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As an example, up-regulation in NHEK after 24 hrs was seen for transcripts encoding CDKN2B (p15), which is believed to be an effector of TGF-?
p15 Binding (encoding) of
1) Confidence 0.35 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1182358 Disease Relevance 0.43 Pain Relevance 0.04
As an example, up-regulation in NHEK after 24 hrs was seen for transcripts encoding CDKN2B (p15), which is believed to be an effector of TGF-?
CDKN2B Binding (encoding) of
2) Confidence 0.35 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1182358 Disease Relevance 0.43 Pain Relevance 0.04
Most recently, four CAD/MI genome wide association studies (GWAS) [10-13] concomitantly identified genetic association of a region on chromosome 9p21.3 adjacent to the cyclin-dependent kinase inhibitor 2A (CDKN2A) and cyclin-dependent kinase inhibitor 2B (CDKN2B) genes within independent MI and CAD populations.
CDKN2B Binding (association) of associated with coronary artery disease and myocardial infarction
3) Confidence 0.30 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2383879 Disease Relevance 1.73 Pain Relevance 0

General Comments

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