INT185074

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.20
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.84
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Bpifa2, Il10) lipid binding (Bpifa2) extracellular space (Il10)
intracellular (Il10) biological_process (Bpifa2)
Anatomy Link Frequency
PSP 3
Bpifa2 (Mus musculus)
Il10 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 105 100.00 Very High Very High Very High
Inflammation 18 13.08 Low Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 126 99.44 Very High Very High Very High
Anaphylaxis 18 58.52 Quite High
Hypersensitivity 45 50.00 Quite Low
Immunization 6 44.92 Quite Low
INFLAMMATION 18 13.08 Low Low
Asthma 9 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Diabetes Mellitus 3 5.00 Very Low Very Low Very Low
Pulmonary Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In NIH mice, OVA induced no changes in cytokines or cell numbers, whereas PSP significantly increased the IL-4 and IL-10 levels (p < 0.007), and OVA+PSP also increased these "responsive" cytokines (p < 0.005, compared to OVA).
PSP Positive_regulation (increased) of IL-10 in PSP associated with cytokine
1) Confidence 0.20 Published 2005 Journal BMC Immunol Section Body Doc Link PMC1182367 Disease Relevance 0.18 Pain Relevance 0.18
However, while IL-4 and IL-10 cytokine responses were significantly increased by OVA+PSP in all three strains, in C3H/HeN mice the levels were low and the increases may not be biologically significant.
PSP Positive_regulation (increased) of IL-10 in PSP associated with sprains and strains and cytokine
2) Confidence 0.13 Published 2005 Journal BMC Immunol Section Body Doc Link PMC1182367 Disease Relevance 0.44 Pain Relevance 0.13
With regard to the cytokines (Figure 3B, C and 3D), OVA+PSP strongly increased the levels of IL-4 and IL-10 compared to the three control groups in BALB/cA mice (p < 0.006), whereas the IFN-?
PSP Positive_regulation (increased) of IL-10 in PSP associated with cytokine
3) Confidence 0.06 Published 2005 Journal BMC Immunol Section Body Doc Link PMC1182367 Disease Relevance 0.22 Pain Relevance 0.18

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox