INT185231

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Context Info
Confidence 0.47
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.79
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
T cells 4
lungs 1
Cd8a (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 9 18.56 Low Low
Inflammation 7 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 82 98.44 Very High Very High Very High
Sprains And Strains 40 98.00 Very High Very High Very High
Infection 121 97.36 Very High Very High Very High
Lymphatic System Cancer 44 91.92 High High
Leukemia 37 91.52 High High
Respiratory Syncytial Virus 64 88.72 High High
Immunization 11 84.40 Quite High
Mastocytoma 1 77.52 Quite High
Influenza Virus Infection 62 70.04 Quite High
Targeted Disruption 3 54.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Assay of CD8+ T cells priming activity
Transcription (activity) of CD8 in T cells
1) Confidence 0.47 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2883599 Disease Relevance 0.15 Pain Relevance 0
These findings suggest that CD11c mRNA is constitutively expressed in CD8+ T cells.


Transcription (expressed) of CD8 in T cells
2) Confidence 0.26 Published 2005 Journal Respir Res Section Body Doc Link PMC1184101 Disease Relevance 0.66 Pain Relevance 0
Although the distributions of the CD4 and CD8 markers were rather stochastic in the tumor cells analyzed, we did find that single positive T–cells were usually skewed towards the CD8+ rather than to the CD4+ lineage.
Transcription (distributions) of CD8 in T-cells associated with cancer
3) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2788417 Disease Relevance 1.14 Pain Relevance 0
Furthermore, high levels of HA-specific CD4 and CD8 T-cells were detected in the lungs of mice immunized with the MVA-HA vaccine construct at the time of challenge with wild type H1N1/CA virus, with a further accumulation of effector T-cells observed in the lungs three days after the challenge.
Transcription (detected) of CD8 in lungs
4) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2922371 Disease Relevance 0.79 Pain Relevance 0
Although WT1/MHC tetramer+CD8+ T cells were not detected in PB before the WT1 peptide vaccination, WT1/MHC tetramer+CD8+ T cells appeared after the second vaccination.
Neg (not) Transcription (detected) of CD8 in T cells
5) Confidence 0.04 Published 2010 Journal International Journal of Medical Sciences Section Body Doc Link PMC2860640 Disease Relevance 0.05 Pain Relevance 0

General Comments

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