INT185234

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Context Info
Confidence 0.66
First Reported 2005
Last Reported 2005
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 8
Disease Relevance 4.83
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itgax)
Anatomy Link Frequency
T cells 6
spleens 1
P815 1
Itgax (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 48 72.96 Quite High
cytokine 24 5.00 Very Low Very Low Very Low
anesthesia 8 5.00 Very Low Very Low Very Low
isoflurane 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 392 99.36 Very High Very High Very High
Respiratory Syncytial Virus 496 98.96 Very High Very High Very High
Viral Infection 64 95.08 Very High Very High Very High
Mastocytoma 8 88.20 High High
INFLAMMATION 40 72.96 Quite High
Hypersensitivity 24 62.84 Quite High
Sprains And Strains 8 52.52 Quite High
Apoptosis 48 42.00 Quite Low
Adhesions 24 14.32 Low Low
Bacterial Respiratory Disease 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CD11c mRNA was neither detectable in P815 cells nor in LA-4 cells.
Neg (neither) Transcription (detectable) of CD11c in P815
1) Confidence 0.66 Published 2005 Journal Respir Res Section Body Doc Link PMC1184101 Disease Relevance 0.64 Pain Relevance 0
Surprisingly, CD11c mRNA could also be detected in comparable amounts in CD8+ cells isolated from spleens of naïve mice (relative expression = 1.12 ± 0.08).
Transcription (detected) of CD11c in spleens
2) Confidence 0.66 Published 2005 Journal Respir Res Section Body Doc Link PMC1184101 Disease Relevance 0.73 Pain Relevance 0
Furthermore CD11c mRNA was detectable in resting as well as activated CD8+ T cells.
Transcription (detectable) of CD11c in T cells
3) Confidence 0.66 Published 2005 Journal Respir Res Section Body Doc Link PMC1184101 Disease Relevance 0.74 Pain Relevance 0.07
Contamination by CD11c+ non-T cells cannot be excluded completely but is very unlikely to account for CD11c mRNA detection in CD8 T cells since no major difference in CD11c mRNA quantity was detected between CD8+ and CD11c+ cell populations.
Transcription (detection) of CD11c in T cells
4) Confidence 0.66 Published 2005 Journal Respir Res Section Body Doc Link PMC1184101 Disease Relevance 0.58 Pain Relevance 0.06
These findings suggest that CD11c mRNA is constitutively expressed in CD8+ T cells.


Transcription (expressed) of CD11c in T cells
5) Confidence 0.66 Published 2005 Journal Respir Res Section Body Doc Link PMC1184101 Disease Relevance 0.66 Pain Relevance 0
CD11c mRNA seems to be expressed constitutively in CD8+ T cells while expression of CD11c protein on the cell surface requires activation.
Transcription (expressed) of CD11c in T cells
6) Confidence 0.63 Published 2005 Journal Respir Res Section Body Doc Link PMC1184101 Disease Relevance 0.49 Pain Relevance 0.06
Contamination by CD11c+ non-T cells cannot be excluded completely but is very unlikely to account for CD11c mRNA detection in CD8 T cells since no major difference in CD11c mRNA quantity was detected between CD8+ and CD11c+ cell populations.
Neg (no) Transcription (detected) of CD11c in T cells
7) Confidence 0.49 Published 2005 Journal Respir Res Section Body Doc Link PMC1184101 Disease Relevance 0.56 Pain Relevance 0.06
CD11c mRNA is expressed by both activated and resting CD8+ T cells
Transcription (expressed) of CD11c in T cells
8) Confidence 0.49 Published 2005 Journal Respir Res Section Body Doc Link PMC1184101 Disease Relevance 0.42 Pain Relevance 0

General Comments

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