INT185285

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Context Info
Confidence 0.43
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.12
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CDKN2A) DNA binding (CDKN2A) protein complex (CDKN2A)
cytoplasm (CDKN2A) cytosol (CDKN2A) nucleolus (CDKN2A)
CDKN2A (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 31 100.00 Very High Very High Very High
Congenital Anomalies 2 92.40 High High
Skin Cancer 1 83.68 Quite High
Glioma 1 82.24 Quite High
Pancreatic Ductal Carcinoma 2 79.20 Quite High
Pancreatic Cancer 15 76.32 Quite High
Adenocarcinoma 8 64.00 Quite High
Retinoblastoma 1 57.64 Quite High
Malignant Neoplastic Disease 2 27.36 Quite Low
Aggression 1 24.64 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DNA hypermethylation can inhibit transcription of tumor suppressor genes and mismatch repair genes (p16, hMLH1 and VHL), providing an epigenetic mechanism of selection during tumorigenesis [11,12].
Negative_regulation (inhibit) of Transcription (transcription) of p16 associated with cancer
1) Confidence 0.43 Published 2005 Journal BMC Gastroenterol Section Body Doc Link PMC1185532 Disease Relevance 1.12 Pain Relevance 0

General Comments

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