INT185299

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.22
First Reported 2005
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 6.35
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (PNKD) nucleus (PNKD) cytoplasm (PNKD)
Anatomy Link Frequency
neuronal 1
PNKD (Homo sapiens)
PNKD - G2019S (1)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 8 36.80 Quite Low
fibrosis 8 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Abeta 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Dopamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperplasia 136 100.00 Very High Very High Very High
Pancreatic Ductal Carcinoma 136 100.00 Very High Very High Very High
Helminth Infection 72 98.86 Very High Very High Very High
Toxicity 64 97.44 Very High Very High Very High
Metaplasia 4 93.76 High High
Targeted Disruption 72 93.36 High High
Disease 48 91.32 High High
Pancreatitis 16 77.76 Quite High
Creutzfeldt Jakob Disease 2 61.04 Quite High
Kuru 1 60.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expressions of the apomucins, Ki67 and p53 in MGH and PDC in the present study matched mostly those of other reports [20,21,23-26].
Gene_expression (expressions) of PDC associated with pancreatic ductal carcinoma and hyperplasia
1) Confidence 0.22 Published 2005 Journal J Carcinog Section Body Doc Link PMC1185555 Disease Relevance 1.18 Pain Relevance 0
Namely, the IC adjacent to the atypical MGH (PanIN-1B), which is sometimes proliferative cell, had the mucin phenotypic expression and high frequency of K-ras mutation as well as PDC.
Gene_expression (expression) of PDC associated with pancreatic ductal carcinoma and hyperplasia
2) Confidence 0.17 Published 2005 Journal J Carcinog Section Body Doc Link PMC1185555 Disease Relevance 1.67 Pain Relevance 0
Therefore, it is very important to know the characteristics of pre-cancerous lesion of PDC for the preventive medicine and the early detection of PDC.
Gene_expression (detection) of PDC associated with pancreatic ductal carcinoma
3) Confidence 0.15 Published 2005 Journal J Carcinog Section Body Doc Link PMC1185555 Disease Relevance 1.34 Pain Relevance 0
And the results in the present study indicated that the mucin phenotypes of the atypical MGH (PanIN-1B by PanIN system) had a diffusely positive reaction for both anti-MUC1 staining and anti-45M1 staining, and had a spasely positive reaction for anti-Ki-67 staining, and these findings resembled those of the pancreatic ductal carcinoma (PDC), except for the expression of p53 (MGH: negative, PDC: positive).
Neg (except) Gene_expression (expression) of PDC associated with pancreatic ductal carcinoma and hyperplasia
4) Confidence 0.15 Published 2005 Journal J Carcinog Section Body Doc Link PMC1185555 Disease Relevance 1.16 Pain Relevance 0
Saha et al [63] have recently shown that knockdown of lrk-1 sensitizes worms to the mitochondrial toxic rotenone, while pan-neuronal expression of wild type human or G2019S fPD LRRK2 (driven by the snb-1 promoter) protects against rotenone toxicity.
Gene_expression (expression) of fPD (G2019S) in neuronal associated with toxicity and helminth infection
5) Confidence 0.01 Published 2009 Journal Mol Neurodegener Section Body Doc Link PMC2762972 Disease Relevance 1.00 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox