INT185337

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Context Info
Confidence 0.22
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.39
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (GLUL) small molecule metabolic process (GLUL) lyase activity (GLUL)
Golgi apparatus (GLUL) intracellular (GLUL) ligase activity (GLUL)
Anatomy Link Frequency
chondrocytes 2
GLUL (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 27 98.52 Very High Very High Very High
adenocard 2 96.28 Very High Very High Very High
cytokine 8 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
ischemia 6 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 18 99.84 Very High Very High Very High
Osteoarthritis 27 98.52 Very High Very High Very High
Disease 6 23.44 Low Low
Stress 9 16.12 Low Low
INFLAMMATION 9 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 6 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Fatigue 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We selected two proteins, possibly involved in the OA process, on which to perform additional studies in order to verify their altered expression in GS and CS-treated chondrocytes: GRP78 and SOD2.
Regulation (altered) of Gene_expression (expression) of GS in chondrocytes associated with osteoarthritis
1) Confidence 0.22 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945029 Disease Relevance 0.19 Pain Relevance 0.10
GS glutamine synthetase

Authors' contributions

Regulation (contributions) of Gene_expression (synthetase) of glutamine
2) Confidence 0.06 Published 2005 Journal BMC Physiol Section Body Doc Link PMC1187899 Disease Relevance 0.20 Pain Relevance 0.10

General Comments

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