INT185401

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Context Info
Confidence 0.27
First Reported 2005
Last Reported 2005
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 4.69
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PVRL1) cell adhesion (PVRL1) plasma membrane (PVRL1)
Anatomy Link Frequency
monocytes 2
PVRL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 25 96.76 Very High Very High Very High
Inflammatory marker 5 91.92 High High
Versed 5 72.00 Quite High
anesthesia 5 69.60 Quite High
cytokine 20 5.00 Very Low Very Low Very Low
Inflammatory mediators 15 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Disease 200 99.52 Very High Very High Very High
INFLAMMATION 45 96.76 Very High Very High Very High
Infection 10 96.48 Very High Very High Very High
Nicotine Addiction 330 94.24 High High
Sleep Disorders 5 73.12 Quite High
Bacterial Infection 5 47.12 Quite Low
Lower Respiratory Tract Infection 5 37.20 Quite Low
Congenital Anomalies 5 33.28 Quite Low
Disease 10 5.00 Very Low Very Low Very Low
Necrosis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A change in the PRR expression on AM from COPD patients may therefore be involved in the process of continuing inflammation and bacterial colonization.
Regulation (change) of Gene_expression (expression) of PRR associated with pulmonary disease and inflammation
1) Confidence 0.27 Published 2005 Journal Respir Res Section Body Doc Link PMC1187924 Disease Relevance 0.58 Pain Relevance 0.08
Regulation of PRR expression on AM
Regulation (Regulation) of Gene_expression (expression) of PRR
2) Confidence 0.27 Published 2005 Journal Respir Res Section Body Doc Link PMC1187924 Disease Relevance 1.29 Pain Relevance 0
To study the regulation of PRR expression after ligand stimulation, cells were exposed to LPS (1 ?
Regulation (regulation) of Gene_expression (expression) of PRR
3) Confidence 0.27 Published 2005 Journal Respir Res Section Body Doc Link PMC1187924 Disease Relevance 1.25 Pain Relevance 0
In our study we asked whether chronic cigarette smoke exposure alters the expression of PRR's in human monocytes/AM ex vivo.
Spec (whether) Regulation (alters) of Gene_expression (expression) of PRR in monocytes
4) Confidence 0.12 Published 2005 Journal Respir Res Section Body Doc Link PMC1187924 Disease Relevance 0.68 Pain Relevance 0.07
In the non-smoker group two age groups were recruited to exclude an age specific effect of PRR expression (young [A], elderly [B]).
Regulation (effect) of Gene_expression (expression) of PRR
5) Confidence 0.12 Published 2005 Journal Respir Res Section Body Doc Link PMC1187924 Disease Relevance 0.88 Pain Relevance 0.18

General Comments

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