INT185440

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Context Info
Confidence 0.20
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.02
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural constituent of ribosome (CYLD) ribosome (CYLD) intracellular (CYLD)
cytoplasm (CYLD) cytosol (CYLD) peptidase activity (CYLD)
Anatomy Link Frequency
vein 2
CYLD (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 24 61.20 Quite High
Inflammatory response 3 45.48 Quite Low
spastic colon 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Calcitonin gene-related peptide 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 8 100.00 Very High Very High Very High
Crohn's Disease 109 98.04 Very High Very High Very High
Disease 40 73.92 Quite High
Injury 2 72.68 Quite High
Inflammatory Bowel Disease 78 71.04 Quite High
INFLAMMATION 24 61.20 Quite High
Gastrointestinal Disease 1 14.08 Low Low
Cancer 9 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low
Colon Cancer 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the same vein, the marked down-regulation of CYLD is of interest as this gene has been identified as a key negative regulator of nuclear factor-kappa B (NF-?
Negative_regulation (down) of Negative_regulation (regulation) of CYLD in vein associated with skin cancer
1) Confidence 0.20 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1188246 Disease Relevance 1.02 Pain Relevance 0.08

General Comments

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