INT185516

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Context Info
Confidence 0.14
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Igfbp2, Csf2) extracellular region (Igfbp2, Csf2) signal transduction (Igfbp2)
aging (Igfbp2) response to stress (Igfbp2)
Anatomy Link Frequency
neurons 1
Igfbp2 (Rattus norvegicus)
Csf2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cerebral cortex 5 98.36 Very High Very High Very High
ischemia 6 97.28 Very High Very High Very High
Central nervous system 7 5.00 Very Low Very Low Very Low
Central grey 6 5.00 Very Low Very Low Very Low
midbrain 5 5.00 Very Low Very Low Very Low
Glutamate 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 4 97.28 Very High Very High Very High
Reprotox - General 1 1 97.20 Very High Very High Very High
Hypoxia 5 97.10 Very High Very High Very High
Injury 5 26.48 Quite Low
Pressure And Volume Under Development 2 19.44 Low Low
Urological Neuroanatomy 6 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 4 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Pituitary Cancer 1 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the basis of these data and the earlier study [37], the authors suggested for this model of hypoxia-ischemia that: 1) such patterns of IGF-1 distribution were not compatible with simple diffusion and were likely to be abnormal; 2) bulk flow of CSF through the ependyma and along white matter tracts and also through the subarachnoidal perivascular spaces carried IGF-1, in some cases in association with IGFBP-2, to the neurons and glia of the injured cerebral cortex; and 3) this abnormal flow of CSF promotes the delivery of intraventricularly administered therapeutic agents to damaged tissue sites.
IGFBP-2 Binding (association) of CSF in neurons associated with hypoxia, ischemia, cerebral cortex and reprotox - general 1
1) Confidence 0.14 Published 2005 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC1190198 Disease Relevance 0.29 Pain Relevance 0.17

General Comments

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