INT185666

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Context Info
Confidence 0.33
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.19
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (AR) transport (AR) enzyme binding (AR)
DNA binding (AR) cell-cell signaling (AR) cytoplasm (AR)
AR (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 7 84.08 Quite High
addiction 5 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Carcinoma 1 66.08 Quite High
Lung Cancer 1 64.44 Quite High
Prostate Cancer 27 62.44 Quite High
Breast Cancer 1 23.72 Low Low
Targeted Disruption 12 5.00 Very Low Very Low Very Low
Cancer 12 5.00 Very Low Very Low Very Low
Hypersensitivity 7 5.00 Very Low Very Low Very Low
Hypertrophy 6 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although several studies have determined either the ligand binding affinity of AR or the trans-activation of AR, there are few studies dealing with both aspects.
Positive_regulation (activation) of AR Binding (affinity) of
1) Confidence 0.33 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1192819 Disease Relevance 0.07 Pain Relevance 0.04
In addition to direct AR binding, PI3K (and subsequently TOR) can be activated through receptor adaptor complexes such as those associated with Her2.
Positive_regulation (activated) of AR Binding (binding) of
2) Confidence 0.22 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2812491 Disease Relevance 0.13 Pain Relevance 0

General Comments

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