INT18572

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Context Info
Confidence 0.53
First Reported 1990
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 1.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (HERPUD1) molecular_function (HERPUD1) response to stress (HERPUD1)
Anatomy Link Frequency
brain 2
HERPUD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 3 99.92 Very High Very High Very High
narcan 3 99.38 Very High Very High Very High
opiate 18 96.04 Very High Very High Very High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Naloxone and DAMGO were ineffective at inhibiting Tyr-MIF-1 binding.
Negative_regulation (inhibiting) of Tyr-MIF-1 Binding (binding) of associated with narcan
1) Confidence 0.53 Published 1990 Journal Life Sci. Section Abstract Doc Link 1976197 Disease Relevance 0 Pain Relevance 0.59
Novel peptides with opiate activity, derived from endogenous sources (human and bovine casomorphins from milk, hemorphins from hemoglobin, and cytochrophins from mitochondrial cytochrome b), were tested for their ability to inhibit binding of the brain peptide Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) to its high affinity sites in rat brain.
Negative_regulation (inhibit) of Tyr-MIF-1 Binding (binding) of in brain associated with opiate
2) Confidence 0.46 Published 1990 Journal Life Sci. Section Abstract Doc Link 1976197 Disease Relevance 0 Pain Relevance 0.50
The order of potency in inhibiting binding of 125I-Tyr-MIF-1 was: hemorphin and bovine casomorphins greater than Tyr-MIF-1 greater than cytochrophins greater than human casomorphins.
Negative_regulation (inhibiting) of Tyr-MIF-1 Binding (binding) of associated with potency
3) Confidence 0.39 Published 1990 Journal Life Sci. Section Abstract Doc Link 1976197 Disease Relevance 0 Pain Relevance 0.54

General Comments

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