INT185723

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Context Info
Confidence 0.04
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.11
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (GATA4) nucleus (GATA4) DNA binding (GATA4)
transcription factor binding (GATA4) cell-cell signaling (GATA4)
Anatomy Link Frequency
patterning 2
GATA4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dynorphin 7 99.94 Very High Very High Very High
Kinase C 4 99.08 Very High Very High Very High
agonist 3 78.96 Quite High
opioid receptor 3 77.44 Quite High
complementary and alternative medicine 27 5.00 Very Low Very Low Very Low
Acupuncture 13 5.00 Very Low Very Low Very Low
ischemia 5 5.00 Very Low Very Low Very Low
electroacupuncture 4 5.00 Very Low Very Low Very Low
Kappa opioid receptor 3 5.00 Very Low Very Low Very Low
Opioid 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 5 57.76 Quite High
Embryonal Carcinoma 2 16.12 Low Low
Disease 5 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 4 5.00 Very Low Very Low Very Low
Coronary Artery Disease 2 5.00 Very Low Very Low Very Low
Hypertrophy 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low
Bone Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This finding is particularly rewarding since we have shown that the prodynorphin gene and dynorphin B primed GATA-4 and Nkx-2.5 transcription (29,30) and triggered protein kinase C (PKC) signaling through complex subcellular redistribution patterning of targeted PKC isozymes, another major requirement for ES cell commitment to the cardiac lineage (30).
Regulation (primed) of Transcription (transcription) of GATA-4 in patterning associated with kinase c and dynorphin
1) Confidence 0.04 Published 2005 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1193541 Disease Relevance 0.11 Pain Relevance 0.40

General Comments

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