INT185731

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Context Info
Confidence 0.34
First Reported 2005
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.89
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Tnfsf11) extracellular space (Tnfsf11) extracellular region (Tnfsf11)
plasma membrane (Tnfsf11) intracellular (Tnfsf11) response to stress (Tnfsf11)
Tnfsf11 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 5 50.00 Quite Low
Potency 5 44.84 Quite Low
Bioavailability 5 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
complementary and alternative medicine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Respiratory Syncytial Virus 116 100.00 Very High Very High Very High
Osteoporosis 29 99.56 Very High Very High Very High
Fibromyalgia 6 53.68 Quite High
Bone Cancer 4 20.84 Low Low
Hypercalcemia 18 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
Multiple Myeloma 6 5.00 Very Low Very Low Very Low
Toxicity 4 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Postmenopausal Osteoporosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that HEP extract might inhibit osteoclastogenesis via the modulation of the OPG/RANKL system in osteoblastic cells.
Spec (might) Negative_regulation (inhibit) of Spec (might) Regulation (modulation) of RANKL associated with osteoporosis
1) Confidence 0.34 Published 2005 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1193542 Disease Relevance 0.32 Pain Relevance 0
B, whereas 7-day treatment resulted in an inhibitory effect as previously reported [10].Fig. 4Effect of RSV and its analogues on RANKL-mediated NF-?
Negative_regulation (reported) of Regulation (analogues) of RANKL associated with respiratory syncytial virus
2) Confidence 0.18 Published 2010 Journal Calcif Tissue Int Section Body Doc Link PMC2964465 Disease Relevance 0.57 Pain Relevance 0

General Comments

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