INT185732

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Context Info
Confidence 0.31
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.39
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnfrsf11b) extracellular space (Tnfrsf11b) extracellular region (Tnfrsf11b)
proteinaceous extracellular matrix (Tnfrsf11b) extracellular matrix organization (Tnfrsf11b)
Anatomy Link Frequency
fibroblasts 1
Tnfrsf11b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Bioavailability 1 64.64 Quite High
ischemia 8 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
beta blocker 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
complementary and alternative medicine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 24 86.68 High High
Hypercalcemia 4 50.32 Quite High
Postmenopausal Osteoporosis 2 30.96 Quite Low
Cancer 5 20.80 Low Low
Endometriosis (extended) 3 20.64 Low Low
Coronary Artery Disease 4 9.36 Low Low
Cv Unclassified Under Development 8 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Myocardial Infarction 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ratio of mRNA expression of OPG to RANKL (OPG/RANKL) was calculated to assess its effect on osteoclastogenesis.
Transcription (expression) of OPG
1) Confidence 0.31 Published 2005 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1193542 Disease Relevance 0.39 Pain Relevance 0
The targets of miR-539 obtained by computational analyses include matrix metallopeptidase 20, fibroblast growth factor 14, clathrin, light polypeptide, osteoprotegerin and transcription factors like forkhead box B1, which may have roles in cardiac remodeling. miR-21 were shown to regulate the ERK-MAP kinase signalling pathway in cardiac fibroblasts, which has role on global cardiac structure and function [24].
Transcription (transcription) of osteoprotegerin in fibroblasts
2) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3009730 Disease Relevance 0 Pain Relevance 0.03

General Comments

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