INT185754

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Context Info
Confidence 0.03
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.01
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (INCENP) chromosome segregation (INCENP) chromosome (INCENP)
cytoskeleton (INCENP) nucleus (INCENP) protein complex (INCENP)
Anatomy Link Frequency
blood 2
INCENP (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 1 86.96 High High
Inflammation 24 61.72 Quite High
fibrosis 10 29.52 Quite Low
Inflammatory marker 2 16.28 Low Low
metalloproteinase 11 5.00 Very Low Very Low Very Low
Bioavailability 9 5.00 Very Low Very Low Very Low
COX-2 inhibitor 6 5.00 Very Low Very Low Very Low
melanocortin 1 receptor 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cirrhosis 110 100.00 Very High Very High Very High
Sepsis 3 95.80 Very High Very High Very High
Adhesions 3 90.48 High High
INFLAMMATION 25 86.56 High High
Syndrome 1 80.00 Quite High
Disease 22 79.44 Quite High
Organ Transplantation 1 75.60 Quite High
Atherosclerosis 6 68.88 Quite High
Cardiovascular Disease 9 68.08 Quite High
Urticaria 1 62.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is important to note that the UCUAN sequence significantly reduces interaction with CFIm in vitro (Venkataraman et al, 2005).
Negative_regulation (reduces) of in vitro Binding (interaction) of
1) Confidence 0.03 Published 2010 Journal EMBO J Section Body Doc Link PMC2876958 Disease Relevance 0 Pain Relevance 0
Celecoxib inhibits vascular channel formation in vitro
Negative_regulation (inhibits) of in vitro Binding (formation) of
2) Confidence 0.03 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1797025 Disease Relevance 0.06 Pain Relevance 0
The phenolic compound, hydroxytyrosol has been noted to completely inhibit platelet aggregation in human blood (in vitro) in the range of 100–400 ?
Negative_regulation (inhibit) of in vitro Binding (aggregation) of in blood
3) Confidence 0.02 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2852848 Disease Relevance 0.53 Pain Relevance 0.08
In our studies, we showed that both conjugates were able to effectively reduce the viability of HSC in vitro.
Negative_regulation (reduce) of in vitro Binding (viability) of associated with cirrhosis
4) Confidence 0.02 Published 2007 Journal Pharm Res Section Body Doc Link PMC1915609 Disease Relevance 0.65 Pain Relevance 0
Bres., T. versicolor and P. betulinus inhibit in vitro binding of LPS to the receptor (104) and could therefore contain lead structures for drugs against LPS-mediated septic shock.


Negative_regulation (inhibit) of in vitro Binding (binding) of associated with sepsis
5) Confidence 0.00 Published 2005 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1193547 Disease Relevance 0.77 Pain Relevance 0.04

General Comments

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