INT185807

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Context Info
Confidence 0.56
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SPP1, MMP7) extracellular region (SPP1, MMP7) peptidase activity (MMP7)
proteinaceous extracellular matrix (MMP7) cell adhesion (SPP1) cytoplasm (SPP1)
Anatomy Link Frequency
epithelial cells 1
SPP1 (Homo sapiens)
MMP7 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 72 84.88 Quite High
Inflammation 3 82.64 Quite High
cytokine 5 58.24 Quite High
corticosteroid 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Fibrosis 65 84.88 Quite High
INFLAMMATION 2 82.64 Quite High
Fibrosis 9 79.20 Quite High
Hyperplasia 2 65.76 Quite High
Pulmonary Disease 3 59.84 Quite High
Myocardial Infarction 1 41.40 Quite Low
Keloid Scars 1 36.40 Quite Low
Internal Fibrosis 1 32.64 Quite Low
Disease 6 5.00 Very Low Very Low Very Low
Adhesions 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, osteopontin is cleaved and activated by MMP-7 [31], and we observe that MMP-7 is induced by osteopontin in epithelial cells, suggesting that this positive feedback mechanism is also applicable to osteopontin and MMP-7.
osteopontin Positive_regulation (induced) of MMP-7 in epithelial cells
1) Confidence 0.56 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1198037 Disease Relevance 0.79 Pain Relevance 0.36

General Comments

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