INT185809

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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.69
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (PDX1, SPP1) cytosol (PDX1) extracellular space (SPP1)
generation of precursor metabolites and energy (PDX1) extracellular region (SPP1) cell adhesion (SPP1)
PDX1 (Homo sapiens)
SPP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 144 100.00 Very High Very High Very High
antagonist 2 28.68 Quite Low
cytokine 10 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Fibrosis 130 100.00 Very High Very High Very High
Disease 12 97.48 Very High Very High Very High
Fibrosis 18 90.00 High High
Hyperplasia 4 83.84 Quite High
Adhesions 6 5.00 Very Low Very Low Very Low
Pulmonary Disease 6 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Nicotine Addiction 4 5.00 Very Low Very Low Very Low
Lung Cancer 4 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, our results suggest that in IPF the interaction between MMP-7 and osteopontin may be involved in the relentlessly progressive nature of the disease, and highlight osteopontin as a potential target for therapeutic intervention in this incurable disease.


IPF Binding (interaction) of osteopontin associated with fibrosis and disease
1) Confidence 0.02 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1198037 Disease Relevance 0.84 Pain Relevance 0.28
Furthermore, our results suggest that in IPF the interaction between MMP-7 and osteopontin may be involved in the relentlessly progressive nature of the disease, and highlight osteopontin as a potential target for therapeutic intervention in this incurable disease.


IPF Binding (interaction) of osteopontin associated with fibrosis and disease
2) Confidence 0.02 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1198037 Disease Relevance 0.84 Pain Relevance 0.28

General Comments

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