INT185818

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Context Info
Confidence 0.10
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.82
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (SPP1, COL7A1) cell adhesion (SPP1, COL7A1) extracellular space (SPP1)
cytoplasm (SPP1)
Anatomy Link Frequency
myocardium 2
fibroblasts 2
SPP1 (Homo sapiens)
COL7A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 144 94.08 High High
cytokine 10 85.52 High High
Inflammation 6 37.04 Quite Low
corticosteroid 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 2 96.00 Very High Very High Very High
Pulmonary Fibrosis 130 94.48 High High
Keloid Scars 2 91.00 High High
Internal Fibrosis 2 87.24 High High
Fibrosis 18 84.12 Quite High
Pulmonary Disease 6 82.72 Quite High
Hyperplasia 4 70.80 Quite High
INFLAMMATION 4 37.04 Quite Low
Adhesions 6 21.16 Low Low
Disease 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, osteopontin appears to be an important mediator of the cardiac profibrotic effects of angiotensin II by promoting collagen synthesis and remodeling in the interstitial myocardium [26].
osteopontin Positive_regulation (promoting) of Gene_expression (synthesis) of collagen in myocardium
1) Confidence 0.10 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1198037 Disease Relevance 0.82 Pain Relevance 0.28
Osteopontin induces collagen gene expression in fibroblasts
Osteopontin Positive_regulation (induces) of Gene_expression (expression) of collagen in fibroblasts
2) Confidence 0.10 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1198037 Disease Relevance 0 Pain Relevance 0

General Comments

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