INT185820

Context Info Confidence 0.41 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.72 Pain Relevance 0.33

peptidase activity (MMP7) extracellular space (MMP7) extracellular region (MMP7) proteinaceous extracellular matrix (MMP7)

Anatomy Link Frequency epithelial cells 2 MMP7 (Homo sapiens)

Pain Link Frequency Relevance Heat fibrosis 72 99.20 Inflammation 3 76.24 cytokine 5 51.84 corticosteroid 2 5.00 anesthesia 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Pulmonary Fibrosis 65 99.20 INFLAMMATION 2 76.24 Fibrosis 9 72.80 Hyperplasia 2 59.36 Pulmonary Disease 3 53.44 Myocardial Infarction 1 35.00 Keloid Scars 1 30.00 Internal Fibrosis 1 26.24 Disease 6 5.00 Adhesions 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

This is also supported by the colocalization of MMP-7 and osteopontin in IPF epithelial cells, and by the computational relationship of the expression levels of osteopontin and MMP-7.

Positive_regulation (supported) of Localization (colocalization) of MMP-7 in epithelial cells associated with fibrosis

1) Confidence 0.41 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1198037 Disease Relevance 0.72 Pain Relevance 0.33

General Comments

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