INT18593

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Context Info
Confidence 0.11
First Reported 1990
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.08
Pain Relevance 2.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Sst) oxidoreductase activity (Fdft1) extracellular region (Sst)
endoplasmic reticulum (Fdft1) transferase activity, transferring alkyl or aryl (other than methyl) groups (Fdft1)
Anatomy Link Frequency
hippocampus 2
Sst (Rattus norvegicus)
Fdft1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 33 100.00 Very High Very High Very High
antagonist 3 99.70 Very High Very High Very High
Hippocampus 8 99.66 Very High Very High Very High
agonist 2 98.68 Very High Very High Very High
Clonidine 9 98.02 Very High Very High Very High
Neuropeptide 1 91.32 High High
tetrodotoxin 1 78.08 Quite High
Calcium channel 2 75.40 Quite High
conotoxin 1 72.12 Quite High
Disease Link Frequency Relevance Heat
Decapitation 1 78.00 Quite High
Bordatella Infection 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results suggest that in the rat hippocampus, both SS-28 and SS-14 interact with SS receptors to regulate ACh release indirectly by a mechanism that involves alterations of calcium influx during depolarization.
SS-14 Binding (interact) of SS in hippocampus associated with somatostatin and hippocampus
1) Confidence 0.11 Published 1990 Journal J. Neurochem. Section Abstract Doc Link 1976754 Disease Relevance 0 Pain Relevance 1.14
We studied whether clonidine, an alpha 2-adrenoceptor agonist, and yohimbine, an alpha 2-adrenoceptor antagonist, can modulate somatostatin-like immunoreactivity (SSLI) levels, binding of 125I-Tyr11-somatostatin (125I-Tyr11-SS) to its specific receptors, SS-inhibited adenylyl cyclase (AC) activity, and the guanine-nucleotide binding regulatory proteins Gi and G(o) in the rat hippocampus.
somatostatin Binding (binding) of SS in hippocampus associated with antagonist, somatostatin, agonist, hippocampus and clonidine
2) Confidence 0.07 Published 1995 Journal Neuropsychopharmacology Section Abstract Doc Link 7766286 Disease Relevance 0.08 Pain Relevance 0.98

General Comments

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