INT185934

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Context Info
Confidence 0.79
First Reported 2005
Last Reported 2005
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.17
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Calm-ps1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 14 91.44 High High
Inflammatory response 20 50.00 Quite Low
Inflammation 66 41.92 Quite Low
interstitial cystitis 52 5.00 Very Low Very Low Very Low
IPN 18 5.00 Very Low Very Low Very Low
agonist 16 5.00 Very Low Very Low Very Low
hyperexcitability 10 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 102 91.04 High High
Interstitial Cystitis 52 5.00 Very Low Very Low Very Low
Disease 18 5.00 Very Low Very Low Very Low
Inflammatory Pain 18 5.00 Very Low Very Low Very Low
Pain 8 5.00 Very Low Very Low Very Low
Overactive Bladder 6 5.00 Very Low Very Low Very Low
Bladder Disease 6 5.00 Very Low Very Low Very Low
Pollakiuria 4 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low
Hyperalgesia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we examined the isoproterenol mediated phosphorylation state of the cAMP responsive element binding protein (CREB) in the absence and presence of selective concentrations of H-89 or Rp-cAMPS.
Spec (examined) Phosphorylation (phosphorylation) of cAMPS
1) Confidence 0.79 Published 2005 Journal Cell Commun Signal Section Body Doc Link PMC1198236 Disease Relevance 0.08 Pain Relevance 0.04
Since our results reveal no changes in the amount of ERK phosphorylation or induction of COX-2 and iNOS after pretreatment with selective concentrations of H-89 or Rp-cAMPS, it was necessary to confirm that these PKA inhibitors were being used effectively in our system.
Phosphorylation (phosphorylation) of cAMPS
2) Confidence 0.79 Published 2005 Journal Cell Commun Signal Section Body Doc Link PMC1198236 Disease Relevance 0.09 Pain Relevance 0.05

General Comments

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