INT186098

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Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (EGF, MAP2K5) cytosol (MAP2K5) extracellular space (EGF)
extracellular region (EGF) nucleus (MAP2K5) plasma membrane (EGF)
Anatomy Link Frequency
arm 1
EGF (Homo sapiens)
MAP2K5 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 28 79.04 Quite High
Inflammation 2 63.92 Quite High
adenocard 1 18.72 Low Low
aspirin 2 5.00 Very Low Very Low Very Low
Immobilon 2 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 3 63.92 Quite High
Colon Cancer 25 62.40 Quite High
Apoptosis 35 47.20 Quite Low
Familial Adenomatous Polyposis 5 39.60 Quite Low
Death 9 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Adenoma 2 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This effect may explain, at least in part, our previous observation that these drugs inhibit basal and EGF-induced activation of the MEK/ERK arm of the EGFR signaling pathway.
EGF Positive_regulation (activation) of MEK in arm
1) Confidence 0.01 Published 2005 Journal J Carcinog Section Body Doc Link PMC1208922 Disease Relevance 0.19 Pain Relevance 0.18

General Comments

This test has worked.

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