INT186144

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Context Info
Confidence 0.29
First Reported 2005
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.07
Pain Relevance 1.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Oxt) extracellular region (Oxt) cytoplasm (Oxt)
Anatomy Link Frequency
blood 2
Oxt (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 15 98.26 Very High Very High Very High
cannabis 3 98.04 Very High Very High Very High
tolerance 13 93.88 High High
Cannabinoid 7 92.80 High High
analgesia 30 92.48 High High
Neuropeptide 5 87.12 High High
antagonist 12 85.52 High High
Cannabinoid receptor 3 82.00 Quite High
addiction 17 80.88 Quite High
Calcium channel 1 73.76 Quite High
Disease Link Frequency Relevance Heat
Opiate Addiction 8 98.44 Very High Very High Very High
Stress 68 91.76 High High
Aggression 3 91.12 High High
Drug Dependence 15 81.28 Quite High
Anxiety Disorder 116 80.44 Quite High
Cannabis Dependence 1 67.40 Quite High
Recurrence 5 54.12 Quite High
Nociception 6 44.12 Quite Low
Targeted Disruption 12 41.36 Quite Low
Cocaine Dependence 1 21.24 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To confirm this GeneChip data, reverse transcription-polymerase chain reaction (RT-PCR) was performed to measure the mRNA expression level of oxytocin in CaMKIV-/- mice (Fig. 5).
Positive_regulation (measure) of Transcription (expression) of oxytocin
1) Confidence 0.29 Published 2005 Journal Mol Pain Section Body Doc Link PMC1208947 Disease Relevance 0.78 Pain Relevance 0.37
To confirm this GeneChip data, reverse transcription-polymerase chain reaction (RT-PCR) was performed to measure the mRNA expression level of oxytocin in CaMKIV-/- mice (Fig. 5).
Positive_regulation (measure) of Transcription (level) of oxytocin
2) Confidence 0.29 Published 2005 Journal Mol Pain Section Body Doc Link PMC1208947 Disease Relevance 0.78 Pain Relevance 0.37
Lithium was found to prevent the cannabis withdrawal syndrome (increased expression of Fos proteins in oxytocin-immunoreactive neurons and increased oxytocin mRNA expression / increased oxytocin levels in the peripheral blood).
Positive_regulation (increased) of Transcription (expression) of oxytocin in blood associated with cannabis and withdrawal
3) Confidence 0.06 Published 2007 Journal Indian Journal of Psychiatry Section Body Doc Link PMC2917090 Disease Relevance 0.50 Pain Relevance 0.91

General Comments

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