INT186146

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.41
First Reported 2005
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.29
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (GJA1) Golgi apparatus (GJA1) endoplasmic reticulum (GJA1)
cell-cell signaling (GJA1) cytoplasm (GJA1) signal transducer activity (GJA1)
Anatomy Link Frequency
vesicle 1
GJA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
analgesia 15 98.16 Very High Very High Very High
amygdala 2 52.72 Quite High
Dismenorea 5 41.12 Quite Low
Eae 4 35.76 Quite Low
antagonist 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
tail-flick 4 5.00 Very Low Very Low Very Low
withdrawal 3 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
antidepressant 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 34 97.44 Very High Very High Very High
Anxiety Disorder 58 95.92 Very High Very High Very High
Cancer 1 77.72 Quite High
Schizophrenia 1 76.76 Quite High
Disease 1 75.88 Quite High
Targeted Disruption 4 54.60 Quite High
Dysmenorrhea 5 41.12 Quite Low
Premature Birth 3 5.00 Very Low Very Low Very Low
Post-traumatic Stress Disorder 3 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, other genes found to be reduced in CaMKIV-/- mice include the intracellular transportor gene, transthyretin; secretory vesicle protein, synaptotagmin 1, and a gap junction protein, connexin 43.
Negative_regulation (reduced) of connexin 43 in vesicle
1) Confidence 0.41 Published 2005 Journal Mol Pain Section Body Doc Link PMC1208947 Disease Relevance 1.29 Pain Relevance 0.18
Moreover, activation of LHCGR in human myometrial cells leads to loss of gap junction formation and downregulation of GJA1 protein by a PRKA mediated effect [46].
Negative_regulation (downregulation) of GJA1 protein
2) Confidence 0.40 Published 2007 Journal BMC Pregnancy Childbirth Section Body Doc Link PMC1892059 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox